Description

3-Cyano-4-Fluorobenzeneboronic Acid is a versatile and high-value boronic acid derivative, serving as a critical building block in modern synthetic chemistry. Its core value lies in enabling precise carbon-carbon bond formation via the Suzuki-Miyaura cross-coupling reaction, a cornerstone of pharmaceutical and advanced materials research. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries who require reliable, high-purity intermediates for developing new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds containing biaryl or heterobiaryl structures.
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and insecticides that require specific fluorinated and cyano-substituted aromatic systems.
• Material Science Research: Employed in the development of organic electronic materials, such as OLEDs and semiconductors, where its molecular structure can tune electronic properties.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands used in homogeneous catalysis.
• Chemical Biology Probes: Utilized in the construction of molecular probes and sensors for diagnostic and research applications.
• Custom Synthesis and Contract Manufacturing: A vital reagent for fine chemical and custom synthesis houses serving diverse R&D projects.

Basic Information

Product Name	3-Cyano-4-Fluorobenzeneboronic Acid
CAS No.	214210-21-6
Molecular Formula	C7H5BFNO2
Molecular Weight	164.93 g/mol
Synonyms	(3-Cyano-4-fluorophenyl)boronic acid; 4-Fluoro-3-cyanobenzeneboronic acid; 3-Cyano-4-fluorophenylboronic acid; Boronic acid, B-(3-cyano-4-fluorophenyl)-; 214210-21-6; 3-CN-4-F-C6H3B(OH)2
EINECS	Contact for details

Quality Control

Every batch of 3-Cyano-4-Fluorobenzeneboronic Acid undergoes rigorous analytical testing to ensure it meets the high-purity standards required for sensitive coupling reactions. Our quality assurance protocols are designed to guarantee batch-to-batch consistency and reliability. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment. We adhere to stringent in-house specifications aligned with industry best practices for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation and maintain purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.