Description

2-(tert-Butoxycarbonylamino)Hex-5-Enoic Acid is a versatile and high-purity protected amino acid derivative, essential for advanced organic synthesis. Its primary value lies in serving as a crucial building block for the construction of complex peptide and peptidomimetic structures, offering excellent selectivity and yield. This compound is particularly needed by research institutions and pharmaceutical companies engaged in drug discovery, medicinal chemistry, and the development of novel bioactive molecules.

Application

• Pharmaceutical Intermediates: A key chiral synthon in the synthesis of active pharmaceutical ingredients (APIs) and novel drug candidates.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis (SPPS) to introduce specific amino acid residues with the tert-butoxycarbonyl (Boc) protecting group.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and the design of peptidomimetics for targeting various biological pathways.
• Bioconjugation: The terminal alkene and carboxylic acid functionalities allow for further chemical modifications, useful in linker chemistry and bioconjugate development.
• Chemical Biology Probes: Serves as a precursor for synthesizing labeled or tagged peptides used as probes in biochemical and cellular assays.

Basic Information

Product Name	2-(tert-Butoxycarbonylamino)Hex-5-Enoic Acid
CAS No.	214206-61-8
Molecular Formula	C11H19NO4
Molecular Weight	229.27 g/mol
Synonyms	Boc-5-hexenylglycine; (S)-2-((tert-Butoxycarbonyl)amino)hex-5-enoic acid; (S)-2-(Boc-amino)hex-5-enoic acid; 2-[(tert-Butoxycarbonyl)amino]hex-5-enoic acid; (S)-N-Boc-2-amino-5-hexenoic acid; Boc-Hex(5-enyl)-OH; 5-Hexenoic acid, 2-[(1,1-dimethylethoxy)carbonyl]amino]-; N-Boc-2-amino-5-hexenoic acid
EINECS	Contact for details

Quality Control

Our 2-(tert-Butoxycarbonylamino)Hex-5-Enoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and comprehensive identity confirmation. Certificates of Analysis (COA) detailing all specifications are provided to ensure compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.