Description

(5R,2R)-2,5-Diaminoadipic Acid 2Hcl is a high-purity, stereochemically defined diaminodicarboxylic acid derivative, serving as a critical chiral building block in advanced organic synthesis. Its precise stereochemistry makes it an invaluable intermediate for the development of novel pharmaceuticals, peptide mimetics, and complex bioactive molecules. This compound is essential for research and production in pharmaceutical development, biotechnology, and fine chemical synthesis where strict enantiomeric purity is required.

Application

• Pharmaceutical Intermediate: Key chiral precursor in the synthesis of novel drug candidates, particularly for metabolic and neurological disorders.
• Peptide Synthesis: Building block for incorporating the non-proteinogenic diaminoadipic acid moiety into custom peptides and peptidomimetics.
• Bioconjugation & Linker Chemistry: Utilized in the development of antibody-drug conjugates (ADCs) and other bioconjugates due to its dual amine and carboxylic acid functionalities.
• Chemical Biology Research: Probe and tool compound for studying enzyme mechanisms, particularly those involving lysine metabolism or aminoadipate pathways.
• Catalyst & Ligand Development: Serves as a precursor for chiral ligands and catalysts used in asymmetric synthesis.
• Fine Chemical Production: Intermediate in the multi-step synthesis of complex, high-value specialty chemicals.

Basic Information

Product Name	(5R,2R)-2,5-Diaminoadipic Acid 2Hcl
CAS No.	213686-08-9
Molecular Formula	C6H14N2O4 • 2HCl
Molecular Weight	275.10 g/mol
Synonyms	(2R,5R)-2,5-Diaminoadipic Acid Dihydrochloride; (R,R)-2,5-Diaminoadipic Acid 2HCl; (2R,5R)-2,5-Diaminohexanedioic Acid Dihydrochloride; D-2,5-Diaminoadipic Acid Dihydrochloride (stereospecific); (5R,2R)-2,5-Diaminohexanedioic Acid Dihydrochloride; (R,R)-H2Aad-OH • 2HCl; (2R,5R)-Diaminoadipic Acid 2HCl; Stereoisomer of L-2-Aminoadipic Acid Derivative
EINECS	Contact for details

Quality Control

Our (5R,2R)-2,5-Diaminoadipic Acid 2Hcl is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, confirming identity, purity, and stereochemical integrity.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive). Keep the container tightly sealed in a dry environment to prevent absorption of moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% de (diastereomeric excess)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.