Description

Pth (70-84) (Human) is a specific fragment of the human parathyroid hormone (PTH) peptide, identified by CAS No. 213533-86-9. This high-purity synthetic peptide is critical for advanced biochemical research and pharmaceutical development targeting calcium metabolism and bone disorders. It is primarily utilized by research institutions, diagnostic manufacturers, and biopharmaceutical companies engaged in metabolic studies, assay development, and novel therapeutic discovery.

Application

• Biomedical Research: Used as a reference standard and active agent in studies of parathyroid hormone function, calcium homeostasis, and bone remodeling.
• Diagnostic Development: Serves as a critical antigen and calibrator in the development and validation of immunoassays (e.g., ELISA, RIA) for PTH-related disorders.
• Pharmaceutical R&D: Employed in structure-activity relationship (SAR) studies and as a lead compound for developing novel therapeutics for osteoporosis and hyperparathyroidism.
• Cell Biology Studies: Applied in cell culture and receptor binding assays to investigate PTH receptor (PTH1R) signaling pathways.
• Quality Control: Acts as a system suitability standard in analytical laboratories for method development and quality control of related peptide products.

Basic Information

Product Name	Pth (70-84) (Human)
CAS No.	213533-86-9
Molecular Formula	C78H122N24O22
Molecular Weight	1723.96 g/mol
Synonyms	Parathyroid Hormone (70-84), human; PTH (70-84); hPTH (70-84); Parathyrin (70-84); Parathormone fragment (70-84); H-Ala-Val-Ser-Glu-Ile-Gln-Leu-Met-His-Asn-Leu-Gly-Lys-His-Leu-OH; PTH mid-region fragment
EINECS	Contact for details

Quality Control

Every batch of Pth (70-84) (Human) is manufactured under strict quality management systems and undergoes comprehensive analytical testing. Our products are characterized to ensure identity, purity, and consistency, meeting the stringent requirements for research and development applications. Certificates of Analysis (COA) detailing purity (by HPLC), peptide content, and other critical parameters are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccant and under an inert atmosphere. Allow the vial to reach room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Peptide Content	≥ 80.0%
Amino Acid Analysis	± 10% of theoretical
Water Content (KF)	≤ 5.0%
Acetate Content (HPIC)	≤ 10.0%
Solubility	Soluble in water or dilute acetic acid

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.