Description

n-Methoxy-n-Methyl-4-(Dimethylamino)Benzamide is a high-purity chemical intermediate of significant importance in advanced organic synthesis. Its unique structure, featuring both a Weinreb amide moiety and a dimethylamino group, makes it a versatile building block for the construction of complex molecules. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of active ingredients and novel compounds.

Application

This specialized intermediate serves as a key precursor in several high-value synthetic pathways. Its primary applications include:

• Pharmaceutical Intermediate: Crucial for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging its functional groups for structural diversification.
• Weinreb Amide Applications: Serves as a protected carbonyl equivalent for the controlled introduction of ketones and aldehydes via Grignard or organolithium reactions, preventing over-addition.
• Ligand and Catalyst Development: Acts as a starting material for the creation of novel ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of organic semiconductors and functional dyes due to its electron-donating dimethylamino group.
• Custom Synthesis and Contract Manufacturing: A valuable reagent for custom synthesis houses serving the life sciences industry.

Basic Information

Product Name	n-Methoxy-n-Methyl-4-(Dimethylamino)Benzamide
CAS No.	212956-18-8
Molecular Formula	C12H18N2O2
Molecular Weight	222.28 g/mol
Synonyms	4-(Dimethylamino)-N-methoxy-N-methylbenzamide; N-Methoxy-N-methyl-4-(dimethylamino)benzamide; 4-(Dimethylamino)benzoic acid N-methoxy-N-methylamide; Weinreb amide of 4-(Dimethylamino)benzoic acid; N,4-Dimethyl-N-methoxy-4-aminobenzamide; DMABA-Weinreb amide
EINECS	Contact for details

Quality Control

We supply n-Methoxy-n-Methyl-4-(Dimethylamino)Benzamide in high-purity grades suitable for research and cGMP manufacturing. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, detailing purity, identity, and impurity profiles as confirmed by advanced analytical techniques.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.