Description

Z-2-Abu-Phe-Oet is a specialized amino acid derivative and protected peptide building block, identified by CAS No. 212637-53-1. This high-purity intermediate is critical for ensuring precise molecular assembly and maintaining chiral integrity in complex synthetic workflows. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel peptide-based therapeutics, diagnostics, and biochemical tools.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key protected intermediate for the controlled, sequential construction of custom peptide sequences.
• Pharmaceutical Research & Development: Serves as a crucial building block in the synthesis of peptide drug candidates and active pharmaceutical ingredients (APIs).
• Bioconjugation and Probe Development: Used to introduce specific functional groups or labels into peptides for diagnostic assays and imaging agents.
• Combinatorial Chemistry Libraries: Employed in the generation of diverse peptide libraries for high-throughput screening in drug discovery.
• Biochemical Research: Utilized in academic and industrial labs to study protein-protein interactions, enzyme substrates, and receptor ligands.
• Process Development & Scale-Up: Supports the transition from laboratory-scale research to commercial manufacturing of peptide-based products.

Basic Information

Product Name	Z-2-Abu-Phe-Oet
CAS No.	212637-53-1
Molecular Formula	C23H28N2O5
Molecular Weight	412.48 g/mol
Synonyms	Z-2-Aminobutyryl-Phenylalanine Ethyl Ester; N-Cbz-2-Aminobutyryl-L-Phenylalanine Ethyl Ester; Benzyloxycarbonyl-2-aminobutyryl-phenylalanine ethyl ester; Z-Abu-Phe-OEt; CBZ-2-aminobutyryl-Phe-OEt; Nα-Cbz-2-aminobutyryl-L-phenylalanine ethyl ester; (2S)-2-[[(2S)-2-[(benzyloxy)carbonylamino]butanoyl]amino]-3-phenylpropanoic acid ethyl ester
EINECS	Contact for details

Quality Control

Our Z-2-Abu-Phe-Oet is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification and impurity profiling by HPLC, to ensure it meets the exacting standards required for pharmaceutical research. A Certificate of Analysis (COA) detailing identity, purity (typically ≥98%), and specific tests is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using a desiccant.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.