Description

Z-Thr(Tbu)-Obzl is a protected amino acid derivative widely used as a critical building block in peptide synthesis. This compound is essential for researchers and manufacturers requiring high-purity intermediates to construct complex peptide sequences with precise stereochemistry. It is primarily utilized by the pharmaceutical, biotechnology, and academic research sectors for developing therapeutic peptides, diagnostic agents, and novel bioactive compounds.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key intermediate for the controlled incorporation of threonine into peptide chains.
• Solution-Phase Peptide Synthesis: Used in the synthesis of complex peptides and small proteins in solution.
• Pharmaceutical Research: Serves as a building block for the development of peptide-based drug candidates and active pharmaceutical ingredients (APIs).
• Bioconjugation: Facilitates the site-specific modification of peptides for creating targeted drug delivery systems.
• Combinatorial Chemistry: Employed in libraries for high-throughput screening to discover new bioactive molecules.
• Academic & Industrial R&D: A fundamental reagent for studying peptide structure, function, and metabolism.

Basic Information

Product Name	Z-Thr(Tbu)-Obzl
CAS No.	212632-22-9
Molecular Formula	C22H27NO6
Molecular Weight	401.46 g/mol
Synonyms	N-Carbobenzyloxy-O-tert-butyl-L-threonine Benzyl Ester; Z-O-tert-butyl-L-threonine Benzyl Ester; Cbz-Thr(tBu)-OBzl; Benzyl N-[(benzyloxy)carbonyl]-O-(tert-butyl)-L-threoninate; Nα-Cbz-O-tert-butyl-L-threonine Benzyl Ester; (2S,3R)-2-[[(Benzyloxy)carbonyl]amino]-3-[(2-methylpropan-2-yl)oxy]butanoic acid benzyl ester; Z-L-Thr(tBu)-OBzl; CBZ-THR(TBU)-OBENZYL ESTER
EINECS	Contact for details

Quality Control

Our Z-Thr(Tbu)-Obzl is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for sensitive research and production applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to stringent in-house specifications to meet the demands of GMP-guided synthesis and other critical regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Optical Rotation [α]	Contact for details
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.