Description

2,3-Difluoro-4-Ethoxybenzeneboronic Acid is a high-purity boronic acid derivative, a critical building block in modern synthetic organic chemistry. Its value lies in its role as a versatile coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl structures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, particularly for developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, especially those containing difluorinated aromatic systems.
• Agrochemical Synthesis: Used to create novel herbicides, fungicides, and insecticides with enhanced efficacy and environmental profiles.
• Liquid Crystal & OLED Materials: Serves as a building block for advanced electronic materials used in displays and lighting technologies.
• Polymer Chemistry: Enables the synthesis of specialty polymers and functional materials with tailored properties.
• Chemical Research & Development: A valuable reagent for academic and industrial R&D in cross-coupling methodology and organoboron chemistry.
• Custom Synthesis: Employed in contract manufacturing for the bespoke production of complex organic molecules.

Basic Information

Product Name	2,3-Difluoro-4-Ethoxybenzeneboronic Acid
CAS No.	212386-71-5
Molecular Formula	C8H9BF2O3
Molecular Weight	201.97 g/mol
Synonyms	(2,3-Difluoro-4-ethoxyphenyl)boronic acid; 2,3-Difluoro-4-ethoxybenzeneboronic acid; 4-Ethoxy-2,3-difluorobenzeneboronic acid; B-(2,3-Difluoro-4-ethoxyphenyl)boronic acid; 2,3-Difluoro-4-ethoxybenzeneboronic acid pinacol ester (common derivative); 2,3-Difluoro-4-ethoxy phenylboronic acid
EINECS	Contact for details

Quality Control

Our 2,3-Difluoro-4-Ethoxybenzeneboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for sensitive coupling reactions. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay (NMR)	≥ 95.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.