Description

Gp100 (25-33), Human CAS NO 212370-40-6 is a defined synthetic peptide fragment derived from the human glycoprotein 100 (gp100) melanoma antigen. This high-purity peptide is a critical research tool for immunological studies and therapeutic development, offering precise molecular targeting. It is primarily utilized by biotechnology and pharmaceutical R&D teams focused on oncology, vaccine development, and T-cell receptor (TCR) research.

Application

• Immunological Research: Used as a specific antigen to study T-cell recognition, activation, and immune responses in melanoma.
• Vaccine Development: Serves as a key component in the research and formulation of peptide-based cancer vaccines.
• TCR Characterization: Essential for screening, validating, and characterizing T-cell receptors (TCRs) and engineered T-cells (e.g., TCR-T therapies).
• Biomarker Studies: Employed in assays to detect and quantify gp100-specific immune responses in clinical samples.
• Quality Control & Standardization: Acts as a reference standard in the quality control of diagnostic kits and therapeutic products targeting the gp100 antigen.
• Academic & Preclinical Research: Supports fundamental research into melanoma biology, antigen presentation, and immunotherapy mechanisms.

Basic Information

Product Name	Gp100 (25-33), Human
CAS No.	212370-40-6
Molecular Formula	C50H78N14O13
Molecular Weight	1051.2 g/mol
Synonyms	gp100 (25-33) peptide; Glycoprotein 100 (25-33); Melanoma antigen gp100 peptide (25-33); HLA-A*0201-restricted gp100 epitope; IMDQVPFSV; gp10025-33; gp100:209-217(2M); gp100209-217 (2M); Modified gp100 peptide
EINECS	Contact for details

Quality Control

Every batch of Gp100 (25-33), Human is manufactured under strict quality management systems and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Our products are suitable for research and development applications, with specifications typically meeting or exceeding industry standards for synthetic peptides. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming critical parameters such as assay purity, peptide content, and endotoxin levels.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, it is recommended to store desiccated. Allow the vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80%
Amino Acid Analysis	Within ± 10% of theoretical
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Endotoxin	< 10 EU/mg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.