Description

9H-Fluoren-9-Ylmethyln-[(2S)-4-(Methylsulfanyl)-1-Oxobutan-2-Yl]Carbamate is a specialized, high-purity chemical building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the production of complex molecules, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries for constructing peptide mimetics and other bioactive compounds. The precise stereochemistry and functional groups make it a valuable reagent for targeted synthesis.

Application

• Pharmaceutical Intermediate: Critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), especially those targeting specific enzymatic pathways.
• Peptidomimetic Research: Used to incorporate non-natural amino acid analogs into peptide chains to enhance stability, bioavailability, or biological activity.
• Protease Inhibitor Development: Serves as a core structure or intermediate in the design and synthesis of potential protease inhibitors due to its specific stereocenter and functional groups.
• Chemical Biology Probes: Employed in the creation of labeled or tagged molecules for studying protein-protein interactions and cellular processes.
• Fine Chemical Synthesis: A valuable reagent for custom synthesis and contract manufacturing organizations (CMOs) producing high-value, low-volume specialty chemicals.
• Academic Research: Utilized in university and institutional labs for methodological development in asymmetric synthesis and heterocyclic chemistry.

Basic Information

Product Name	9H-Fluoren-9-Ylmethyln-[(2S)-4-(Methylsulfanyl)-1-Oxobutan-2-Yl]Carbamate
CAS No.	211929-83-8
Molecular Formula	C20H21NO3S
Molecular Weight	355.45 g/mol
Synonyms	Fmoc-Met-OH; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-methionine; Fmoc-L-methionine; (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-4-(methylthio)butanoic acid; N-α-Fmoc-L-methionine; Fmoc-Met; N-Fmoc-L-methionine; L-Methionine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-
EINECS	Contact for details

Quality Control

Our 9H-Fluoren-9-Ylmethyln-[(2S)-4-(Methylsulfanyl)-1-Oxobutan-2-Yl]Carbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for pharmaceutical R&D and cGMP applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (S-isomer)
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.