Description

Z-Asp(Ochex)-Oh CAS NO 211797-21-6 is a protected aspartic acid derivative, specifically featuring an O-cyclohexyl ester protecting group. This compound is a critical building block in the synthesis of complex peptides and peptidomimetics, offering precise control over stereochemistry and reactivity. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers engaged in developing therapeutic agents and bioactive molecules.

Application

• Peptide Synthesis: As a key chiral intermediate for the solid-phase and solution-phase construction of peptide chains.
• Pharmaceutical Research: Used in the development of protease inhibitors, receptor agonists/antagonists, and other drug candidates targeting neurological and metabolic diseases.
• Bioconjugation: Serves as a modified amino acid for creating customized linkers in antibody-drug conjugates (ADCs) and other bioconjugates.
• Chemical Biology: A tool compound for studying enzyme-substrate interactions and designing activity-based probes.
• Material Science: Potential monomer for the synthesis of specialized polyamides or biomimetic polymers with unique properties.

Basic Information

Product Name	Z-Asp(Ochex)-Oh
CAS No.	211797-21-6
Molecular Formula	C₂₂H₃₁NO₆
Molecular Weight	405.49 g/mol
Synonyms	N-Carbobenzyloxy-O-cyclohexyl-L-aspartic acid; Z-L-Aspartic acid β-cyclohexyl ester; Z-Asp(OcHex)-OH; Nα-Z-L-Aspartic acid 4-cyclohexyl ester; (2S)-2-[[(Benzyloxy)carbonyl]amino]-4-(cyclohexyloxy)-4-oxobutanoic acid; Z-Asp(O-Cyclohexyl)-OH; N-Cbz-O-cyclohexyl-L-aspartic acid; CBZ-L-Aspartic acid β-cyclohexyl ester
EINECS	Contact for details

Quality Control

Every batch of Z-Asp(Ochex)-Oh is manufactured under strict quality management systems. We provide comprehensive analytical data to ensure the product meets the high-purity standards required for pharmaceutical research and GMP-grade synthesis. Certificates of Analysis (COA) detailing purity, chiral purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.