Description

Propargyl β-D-Lactoside Heptaacetate is a high-purity, acetylated glycosyl donor derivative featuring a reactive propargyl group. This compound is a critical synthetic intermediate for the chemoselective construction of complex oligosaccharides and glycoconjugates via click chemistry methodologies. It is primarily utilized by research scientists and process development chemists in the pharmaceutical, biotechnology, and diagnostic sectors for advanced glycobiology research and the development of novel therapeutics.

Application

• Glycoconjugate Synthesis: Serves as a key building block for the preparation of neoglycoconjugates, glycopeptides, and glycolipids through copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions.
• Pharmaceutical Intermediate: Used in the research and development of carbohydrate-based drugs, including antiviral agents, vaccine candidates, and targeted drug delivery systems.
• Chemical Biology Probes: Enables the labeling and visualization of biological processes through the synthesis of activity-based probes for studying glycosidases and glycosyltransferases.
• Material Science: Applied in the surface functionalization of nanomaterials and polymers to create bioactive coatings and smart materials.
• Diagnostic Development: Facilitates the creation of carbohydrate arrays and biosensors for pathogen detection and biomarker analysis.

Basic Information

Product Name	Propargyl β-D-Lactoside Heptaacetate
CAS No.	211688-85-6
Molecular Formula	C33H42O19
Molecular Weight	718.68 g/mol
Synonyms	4-O-β-D-Galactopyranosyl-β-D-glucopyranose, 1,2,3,6,2',3',4',6'-octaacetate, 1-propargyl; Propargyl O-β-D-Galactopyranosyl-(1→4)-β-D-glucopyranoside Heptaacetate; 1-Propargyl 2,3,6-tri-O-acetyl-4-O-(2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl)-β-D-glucopyranoside; Lactose Propargyl Heptaacetate; β-Lactose Propargyl Octaacetate Derivative; Glycosyl Donor Acetate; Click Chemistry Sugar Derivative
EINECS	Contact for details

Quality Control

Our Propargyl β-D-Lactoside Heptaacetate is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and optical rotation measurement. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with research-grade specifications. Custom synthesis and purification to meet specific project requirements are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere such as nitrogen or argon to prevent hydrolysis of the acetyl groups. Store away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Specific Optical Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.