Description

4-Fluoro-2,3-Dimethylphenylboronic Acid is a high-purity organoboron compound that serves as a critical building block in modern synthetic chemistry. Its value lies in enabling precise carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex molecules. This boronic acid is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality intermediates for drug discovery, active ingredient synthesis, and specialty polymer development.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing complex biaryl structures.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides through palladium-catalyzed cross-coupling reactions.
• Liquid Crystal & OLED Materials: Building block for creating advanced organic electronic materials used in displays and lighting technologies.
• Polymer Chemistry: Monomer for synthesizing specialty polymers and functional materials with tailored properties.
• Chemical Research & Development: Versatile reagent in academic and industrial R&D labs for exploring new synthetic pathways and creating compound libraries.
• Fine Chemical Production: Intermediate in the multi-step synthesis of complex fine chemicals and specialty flavors/fragrances.

Basic Information

Product Name	4-Fluoro-2,3-Dimethylphenylboronic Acid
CAS No.	211495-31-7
Molecular Formula	C8H10BFO2
Molecular Weight	167.98 g/mol
Synonyms	(4-Fluoro-2,3-dimethylphenyl)boronic acid; 2,3-Dimethyl-4-fluorophenylboronic acid; 4-Fluoro-2,3-dimethylbenzeneboronic acid; B-(4-Fluoro-2,3-dimethylphenyl)boronic acid; 211495-31-7; 4-Fluoro-2,3-dimethylphenyl-B(OH)2; 4-Fluoro-o-xylene-2-boronic acid
EINECS	Contact for details

Quality Control

Our 4-Fluoro-2,3-Dimethylphenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for sensitive coupling reactions. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is sealed under an inert atmosphere (argon or nitrogen) after opening to prevent degradation. Keep away from incompatible materials such as strong oxidizers.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.