Description

2-Oxazolidinone, 3-(2-Fluoro-1-Oxo-2-Propenyl)-4-(1-Methylethyl)-, (4S)- (9Ci) is a specialized chiral oxazolidinone derivative, a key building block in modern organic synthesis. Its value lies in its role as a versatile chiral auxiliary and precursor for synthesizing complex, biologically active molecules with high stereochemical purity. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly those focused on creating novel fluorinated active ingredients. The product is supplied under the CAS registry number 211444-51-8.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), especially those containing fluorine atoms for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the production of advanced, enantiomerically pure pesticides and herbicides, where the specific stereochemistry is crucial for efficacy and environmental safety.
• Chiral Auxiliary: Serves as a highly effective chiral controller in asymmetric synthesis, enabling the construction of complex molecular architectures with precise stereocontrol.
• Fluorinated Compound Research: A valuable scaffold for medicinal chemistry programs exploring the structure-activity relationships of fluorinated drug candidates.
• Fine Chemical Production: Employed in the multi-step synthesis of other high-value, specialty fine chemicals and advanced materials.

Basic Information

Product Name	2-Oxazolidinone, 3-(2-Fluoro-1-Oxo-2-Propenyl)-4-(1-Methylethyl)-, (4S)- (9Ci)
CAS No.	211444-51-8
Molecular Formula	C9H12FNO3
Molecular Weight	201.20 g/mol
Synonyms	(4S)-3-(2-Fluoro-1-oxo-2-propenyl)-4-(1-methylethyl)-2-oxazolidinone; (S)-3-(2-Fluoroacryloyl)-4-isopropyloxazolidin-2-one; 3-(2-Fluoroacryloyl)-4-isopropyl-2-oxazolidinone, (S)-; Evans Chiral Auxiliary derivative; Fluorinated Evans Auxiliary; (S)-4-Isopropyl-3-(2-fluoroacryloyl)oxazolidin-2-one
EINECS	Contact for details

Quality Control

Our 2-Oxazolidinone, 3-(2-Fluoro-1-Oxo-2-Propenyl)-4-(1-Methylethyl)-, (4S)- (9Ci) is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral purity analysis (HPLC), to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) with detailed specifications are provided for each shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.