Description

Brain Derived Acidic Fibroblast Growth Factor (1-11) is a synthetic peptide fragment corresponding to the N-terminal region of the acidic fibroblast growth factor (aFGF or FGF-1). This compound is a critical research tool for studying the structure-activity relationships, receptor binding, and biological functions of FGF-1 in neural development and repair. It is primarily utilized by research scientists and pharmaceutical developers in the fields of neuroscience, regenerative medicine, and cell biology for in vitro and preclinical studies.

Application

• Neuroscience Research: Investigation of neurotrophic effects, neuronal survival, and differentiation in cell culture models.
• Receptor Binding Studies: Used to map the active sites and binding domains of FGF receptors (FGFRs).
• Biochemical Assay Development: Serves as a reference standard or competitive ligand in ELISA, SPR, and other binding assays.
• Structure-Activity Relationship (SAR) Analysis: Essential for understanding the functional core of aFGF and designing peptide mimetics.
• Cell Culture & Tissue Engineering: Potential component in media formulations for stem cell culture and neural tissue engineering applications.
• Pharmaceutical R&D: Preclinical evaluation of neuroprotective agents and therapies targeting FGF signaling pathways.

Basic Information

Product Name	Brain Derived Acidic Fibroblast Growth Factor (1-11)
CAS No.	211362-82-2
Molecular Formula	C53H84N18O17
Molecular Weight	1221.4 g/mol
Synonyms	aFGF (1-11); Acidic Fibroblast Growth Factor Fragment 1-11; FGF-1 (1-11); BD-aFGF (1-11); H2N-PALPEDGGSGAF-COOH; Fibroblast Growth Factor 1, N-terminal peptide; Brain-derived aFGF peptide; Heparin-binding growth factor 1 fragment
EINECS	Contact for details

Quality Control

Our Brain Derived Acidic Fibroblast Growth Factor (1-11) is manufactured under strict quality systems suitable for research use. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing purity (by HPLC), peptide content, and other critical parameters are provided with every shipment to support your research integrity.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. The product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature before opening to minimize moisture absorption. For long-term storage, consider desiccant.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80%
Amino Acid Analysis	± 10% of theoretical
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water or buffer

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.