Description

1-Boc-2-(Methoxy-Methyl-Carbamoyl)Piperidine is a high-purity, protected piperidine derivative serving as a critical building block in advanced organic synthesis. Its value lies in providing a versatile and reactive scaffold for constructing complex molecules, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries who require reliable, high-quality intermediates for API synthesis and novel compound libraries.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and metabolic disorder targets.
• Peptidomimetic Chemistry: Used to introduce constrained piperidine motifs into peptide backbones to enhance metabolic stability and bioavailability.
• Library Synthesis for Drug Discovery: Employed in high-throughput and combinatorial chemistry to generate diverse compound libraries for screening against biological targets.
• Agrochemical Research: Serves as a building block for developing novel herbicides, fungicides, and insecticides with improved efficacy.
• Ligand and Catalyst Development: Utilized in the synthesis of chiral ligands and organocatalysts for asymmetric synthesis applications.
• Custom Synthesis and Contract Manufacturing: A requested intermediate for custom synthesis projects and scale-up services under cGMP or ISO standards.

Basic Information

Product Name	1-Boc-2-(Methoxy-Methyl-Carbamoyl)Piperidine
CAS No.	211310-10-0
Molecular Formula	C14H26N2O4
Molecular Weight	286.37 g/mol
Synonyms	1-Boc-2-[(Methoxy(methyl)carbamoyl)]piperidine; 1-(tert-Butoxycarbonyl)-2-[(methoxy(methyl)carbamoyl)]piperidine; tert-Butyl 2-[(methoxy(methyl)carbamoyl)]piperidine-1-carboxylate; N-Methoxy-N-methyl-1-Boc-piperidine-2-carboxamide; 1-Boc-piperidine-2-carboxylic acid N-methoxy-N-methylamide; Weinreb Amide of 1-Boc-piperidine-2-carboxylic acid; Boc-2-Piperidinecarboxylic Acid N-Methoxy-N-Methylamide; N-(Methoxy-N-methylcarbamoyl)-1-Boc-piperidine
EINECS	Contact for details

Quality Control

Every batch of 1-Boc-2-(Methoxy-Methyl-Carbamoyl)Piperidine is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and development. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity (typically ≥97% by HPLC), and impurity profile. Our quality protocols are designed to support regulatory filings and ensure batch-to-batch consistency for critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive). For long-term storage, consider using desiccants or storing under an inert atmosphere to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.