Description

Glycine (U-13C2, 15N) is a stable isotope-labeled analog of the fundamental amino acid glycine, uniformly labeled with carbon-13 at both carbon positions and with nitrogen-15. This compound is an essential tool for advanced research, enabling precise metabolic pathway tracing, protein structure elucidation, and quantitative analysis via mass spectrometry and NMR spectroscopy. It is critical for scientists in pharmaceutical development, clinical diagnostics, and academic research who require the highest levels of isotopic purity and chemical stability for their isotopic dilution and tracer studies.

Application

• Biomedical Research & Metabolic Studies: Used as a stable isotope tracer to investigate glycine metabolism, one-carbon metabolism, and related biochemical pathways in cell cultures, animal models, and human clinical studies.
• Quantitative Proteomics & Biomarker Discovery: Serves as a precursor for the synthesis of isotopically labeled peptides and internal standards for accurate mass spectrometry-based protein quantification and biomarker validation.
• NMR Spectroscopy: Provides a non-radioactive, sensitive probe for structural biology and dynamic studies of proteins and enzymes where glycine is a key residue.
• Pharmaceutical Development: Employed in drug metabolism and pharmacokinetics (DMPK) studies to track the fate of drug molecules containing glycine moieties.
• Nutritional Science Research: Used in studies examining glycine supplementation, collagen synthesis, and human amino acid requirements.
• Environmental & Geochemical Tracing: Applied in specialized research to understand nitrogen and carbon cycling in environmental systems.

Basic Information

Product Name	Glycine (U-13C2, 15N)
CAS No.	211057-02-2
Molecular Formula	¹³C₂H₅¹⁵NO₂
Molecular Weight	78.05 g/mol
Synonyms	Aminoacetic acid (U-13C2, 15N); Glycine-13C2,15N; [U-13C2,15N]-Glycine; 2-Aminoacetic acid (U-13C2, 15N); Aminoethanoic acid (U-13C2, 15N); Gly (U-13C2, 15N); Glycocoll (U-13C2, 15N); Stable Isotope Labeled Glycine
EINECS	Contact for details

Quality Control

Every batch of Glycine (U-13C2, 15N) is manufactured and analyzed under strict quality systems to ensure exceptional isotopic and chemical purity. Our products undergo rigorous quality testing, including NMR and LC-MS, to ensure compliance with exacting research standards. Certificates of Analysis (COA) detailing isotopic enrichment (atom % 13C and 15N), chemical purity, and specific analytical data are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccation or storage under an inert atmosphere to maintain stability and isotopic integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment (Atom % 13C)	≥ 99%
Isotopic Enrichment (Atom % 15N)	≥ 98%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.