Description

(R)-2-Aminohept-6-Ynoic Acid is a non-proteinogenic amino acid derivative featuring a chiral center and a terminal alkyne functional group. This unique molecular architecture makes it a highly valuable chiral building block and a versatile chemical handle for advanced synthesis. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and biotechnology sectors for applications such as peptide modification, bioconjugation, and the development of novel active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and synthesis of novel drug candidates, particularly for introducing constrained, alkyne-functionalized amino acid motifs.
• Peptidomimetics & Conformationally Restricted Peptides: Used to incorporate alkyne groups into peptide backbones, enabling "click chemistry" for labeling or creating structurally unique peptide analogs with potential therapeutic activity.
• Bioconjugation & Probe Development: The terminal alkyne allows for efficient, site-specific conjugation via copper-catalyzed azide-alkyne cycloaddition (CuAAC), useful for attaching fluorescent tags, biotin, or other payloads to biomolecules.
• Chemical Biology Research: Acts as a metabolic precursor or a tool compound for studying biological pathways, enabling the incorporation of reporter tags into cellular proteins or other biomolecules.
• Ligand & Catalyst Development: Employed in the synthesis of chiral ligands for asymmetric catalysis or as a component in metal-organic frameworks (MOFs) and functional materials.
• Academic & Industrial R&D: A critical reagent for methodological development in organic synthesis and medicinal chemistry within university and corporate R&D laboratories.

Basic Information

Product Name	(R)-2-Aminohept-6-Ynoic Acid
CAS No.	211054-03-4
Molecular Formula	C7H11NO2
Molecular Weight	141.17 g/mol
Synonyms	(R)-2-Amino-6-heptynoic acid; D-2-Aminohept-6-ynoic acid; (2R)-2-Aminohept-6-ynoic acid; (R)-2-Amino-hept-6-ynoic acid; H-6-Yne-D-homoAla-OH; D-Homopropargylglycine; (R)-Hpg
EINECS	Contact for details

Quality Control

Our (R)-2-Aminohept-6-Ynoic Acid is produced under stringent quality management systems. Each batch is subjected to comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure identity, potency, and consistency. Certificates of Analysis (COA) detailing specific results for chiral purity, chemical purity (by HPLC or titration), residual solvents, and other relevant parameters are provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as indicated on the label or COA. This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.