Description

(R)-2-Aminohex-5-Ynoic Acid is a non-proteinogenic amino acid derivative featuring a chiral center and a terminal alkyne functional group. This unique structure makes it a valuable chiral building block and a versatile intermediate for the synthesis of more complex bioactive molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in medicinal chemistry, peptide mimetics development, and the creation of novel chemical entities.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, particularly in oncology and neurology.
• Peptidomimetics & Conjugation: The alkyne group enables efficient click chemistry (e.g., CuAAC) for labeling, bioconjugation, and the construction of peptide-like structures with enhanced properties.
• Asymmetric Synthesis: Serves as a chiral precursor or auxiliary in stereoselective synthesis to introduce the (R)-2-amino acid configuration into target molecules.
• Chemical Biology Probes: Used to develop activity-based probes and molecular tools for studying enzyme function and biological pathways.
• Agrochemical Research: Employed in the synthesis of novel, chiral active ingredients for crop protection.
• Material Science: A potential monomer for creating specialized polymers with tailored functionalities.

Basic Information

Product Name	(R)-2-Aminohex-5-Ynoic Acid
CAS No.	211054-02-3
Molecular Formula	C6H9NO2
Molecular Weight	127.14 g/mol
Synonyms	(R)-2-Amino-5-hexynoic acid; D-2-Amino-5-hexynoic acid; (2R)-2-Aminohex-5-ynoic acid; (R)-2-Amino-hex-5-ynoic acid; 5-Hexynoic acid, 2-amino-, (2R)-; (R)-5-Hexyn-2-ylglycine
EINECS	Contact for details

Quality Control

We maintain a strict quality management system to ensure batch-to-batch consistency and high purity for research and development applications. Our standard grade typically meets a purity specification of ≥97% (by HPLC), with enantiomeric excess (e.e.) verified by chiral analytical methods. A comprehensive Certificate of Analysis (COA) detailing identity, purity, chiral purity, and residual solvent content is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This compound is hygroscopic (moisture-sensitive). For long-term storage, consider storing under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% e.e.
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.