Description

Cart (62-76) (Human, Rat) is a synthetic peptide fragment corresponding to a specific sequence of the CART (Cocaine- and Amphetamine-Regulated Transcript) polypeptide. This compound is a critical research tool for investigating the role of CART peptides in neurobiology, appetite regulation, and reward pathways. It is primarily utilized by pharmaceutical R&D teams, academic neuroscientists, and contract research organizations (CROs) focused on metabolic disorders, addiction research, and central nervous system drug discovery.

Application

• Neuroscience Research: Used as a reference standard or antigen in studies of CART peptide distribution, receptor binding, and signaling mechanisms in the brain.
• Metabolic Disorder Studies: Applied in preclinical research to explore the role of CART in appetite suppression, energy homeostasis, and potential therapeutic targets for obesity.
• Behavioral Pharmacology: Essential for investigating the involvement of CART peptides in reward, motivation, and the neurobiology of addiction to substances like cocaine and amphetamines.
• Immunoassay Development: Serves as a key immunogen for antibody production or as a calibrator in ELISA and RIA kits designed to quantify CART peptide levels in biological samples.
• Cell Signaling Pathways: Utilized in in vitro assays to study intracellular cascades activated by CART peptide fragments in neuronal and endocrine cell lines.
• Academic & Pharmaceutical R&D: A fundamental reagent for basic research and early-stage drug discovery programs targeting CART-related pathways.

Basic Information

Product Name	Cart (62-76) (Human, Rat)
CAS No.	210978-19-1
Molecular Formula	C81H124N22O21S
Molecular Weight	1782.0 g/mol
Synonyms	CART (62-76); CART Peptide (62-76); Human, Rat CART(62-76); Cocaine- and Amphetamine-Regulated Transcript Peptide (62-76); CARTp (62-76); H-Cys-Ile-Leu-His-Lys-Cys-Asn-Glu-Val-Ala-Ala-Thr-Ala-Leu-NH2 (Disulfide bridge: Cys62-Cys67); CAS 210978-19-1
EINECS	Contact for details

Quality Control

Every batch of Cart (62-76) (Human, Rat) is manufactured and analyzed under strict quality protocols to ensure identity, purity, and consistency for research applications. Our standard grade meets specifications typical for high-purity synthetic peptides used in biochemical research. Comprehensive analytical data, including HPLC purity and mass spectrometry (MS) confirmation, is provided with each Certificate of Analysis (COA), which is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store desiccated at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake. For long-term storage, keep under inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Amino Acid Composition	Conforms to theoretical values (±10%)
Peptide Content	≥ 70% (by weight)
Solubility	Soluble in water or dilute acetic acid

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.