Description

Alpha 1(I) Collagen (614-639), Human is a defined, high-purity peptide fragment derived from the human type I collagen α-1 chain. This specific sequence is critical for research into collagen structure, function, and its role in connective tissue disorders. It serves as an essential reference standard and active ingredient for scientists and formulators in advanced biomedical fields. Key industrial users include biopharmaceutical R&D, diagnostic development, and advanced biomaterials engineering.

Application

• Biomedical Research: Used as a precise antigen for immunoassay development, antibody production, and studying collagen metabolism and related diseases.
• Diagnostic Development: Serves as a critical standard and coating antigen in ELISA and other immunoassays for detecting autoantibodies in conditions like rheumatoid arthritis or systemic sclerosis.
• Pharmaceutical R&D: Employed in drug discovery programs targeting collagen-mediated pathways, fibrosis, and wound healing.
• Biomaterial Science: Acts as a bioactive peptide sequence for functionalizing surfaces or incorporating into scaffolds for tissue engineering applications.
• Quality Control: Provides a defined reference material for the quality assurance of collagen-based products and assays.

Basic Information

Product Name	Alpha 1(I) Collagen (614-639), Human
CAS No.	210905-12-7
Molecular Formula	C119H190N36O39
Molecular Weight	~2628.0 g/mol
Synonyms	Human Collagen α-1(I) Chain Fragment 614-639; Collagen Type I Alpha 1 Chain (614-639); COL1A1 (614-639); GPKGQKGEPGKAGPAGPQGPRGQOGVMGFO; Collagen Peptide (Human, Type I, alpha1); Synthetic Collagen Peptide; Fibrous Collagen Peptide Fragment
EINECS	Contact for details

Quality Control

Our Alpha 1(I) Collagen (614-639), Human is produced under stringent conditions to ensure batch-to-batch consistency and high purity, suitable for sensitive research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, sequence verification, and impurity profiles. We adhere to rigorous quality testing protocols, and specifications can be aligned with customer requirements for advanced applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This product is hygroscopic (moisture-sensitive). Allow the vial to reach room temperature in a desiccator before opening to prevent condensation and moisture uptake. For optimal stability, store lyophilized material under inert atmosphere or desiccant.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Amino Acid Sequence	GPKGQKGEPGKAGPAGPQGPRGQOGVMGFO
Sequence Verification (MS)	Confirmed
Molecular Weight	2628.0 ± 2.0 Da
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.