Description

Boc-n-γ-Ethyl-L-Glutamine is a protected amino acid derivative of significant importance in peptide synthesis and medicinal chemistry. This compound serves as a crucial building block for the controlled introduction of the glutamine side chain, enabling the synthesis of complex peptides and peptidomimetics. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors for drug discovery and development projects.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key intermediate for the incorporation of glutamine residues under standard Boc (tert-butoxycarbonyl) chemistry protocols.
• Solution-Phase Peptide Synthesis: Used in the synthesis of peptide fragments and small peptides in solution, offering flexibility in coupling strategies.
• Peptidomimetic Design: Serves as a precursor for creating modified peptide analogs with enhanced stability, bioavailability, or receptor affinity.
• Pharmaceutical Intermediate: A vital raw material in the research and development of therapeutic peptides targeting various diseases.
• Bioconjugation: Can be used to attach peptides or peptide-like structures to other molecules, such as proteins, polymers, or surfaces, for diagnostic or therapeutic applications.
• Chemical Biology Probes: Useful for synthesizing labeled or tagged peptides used as tools to study biological processes and protein interactions.

Basic Information

Product Name	Boc-n-γ-Ethyl-L-Glutamine
CAS No.	210692-65-2
Molecular Formula	C₁₄H₂₆N₂O₆
Molecular Weight	318.37 g/mol
Synonyms	Nα-Boc-Nγ-ethyl-L-glutamine; (S)-2-((tert-Butoxycarbonyl)amino)-5-(ethylamino)-5-oxopentanoic acid; Boc-Gln(Et)-OH; Boc-L-Glutamine Nγ-ethylamide; tert-Butyloxycarbonyl-Nγ-ethyl-L-glutamine; Boc-Nγ-Et-L-Gln-OH; Nα-Boc-Nγ-ethylglutamine; Boc-Glu(NHEt)-OH
EINECS	Contact for details

Quality Control

Our Boc-n-γ-Ethyl-L-Glutamine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and pharmaceutical applications. A comprehensive Certificate of Analysis (COA) detailing purity, chiral purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (L-isomer)
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.