Description

Fmoc-Arg(Mtr)-N(Och3)Ch3 is a specialized, orthogonally protected arginine derivative designed for advanced peptide synthesis. This compound is critical for researchers and manufacturers requiring precise control over side-chain reactivity during solid-phase peptide assembly, particularly for complex or sensitive sequences. It is an essential building block for pharmaceutical R&D, biotechnology, and academic laboratories focused on developing peptide-based therapeutics, diagnostics, and research tools.

Application

• Solid-Phase Peptide Synthesis (SPPS): As a key protected amino acid for the Fmoc/t-Bu strategy, enabling the controlled incorporation of arginine.
• Pharmaceutical Intermediate: For the research and production of peptide drugs targeting cardiovascular, metabolic, and oncological diseases.
• Bioconjugation: Used in the synthesis of peptide-protein or peptide-antibody conjugates for targeted drug delivery systems.
• Combinatorial Chemistry: A valuable reagent in libraries for high-throughput screening to discover new bioactive peptides.
• Peptide Library Construction: For creating diverse arrays of peptides for epitope mapping, vaccine development, and receptor studies.
• Academic & Industrial R&D: Fundamental research tool in biochemistry and medicinal chemistry for studying protein-protein interactions and enzyme mechanisms.

Basic Information

Product Name	Fmoc-Arg(Mtr)-N(Och3)Ch3
CAS No.	210532-73-3
Molecular Formula	C₃₃H₄₀N₆O₇S
Molecular Weight	664.78 g/mol
Synonyms	Fmoc-Arg(Mtr)-N(OMe)Me; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N'-[(4-methoxy-2,3,6-trimethylbenzenesulfonyl)]-Nω-(methoxy)methyl-L-arginine; Fmoc-L-arginine(Mtr)-N(OMe)Me derivative; Fmoc-Arg(Mtr)-N(OCH3)CH3; Nα-Fmoc-Nω-(4-methoxy-2,3,6-trimethylphenylsulfonyl)-Nω'-(methoxymethyl)-L-arginine; Protected Fmoc-Arginine derivative; Fmoc-Arg(Mtr)-N(OMe)-Me; Fmoc-Arg(Mtr)-N(OMe)Me-OH
EINECS	Contact for details

Quality Control

Our Fmoc-Arg(Mtr)-N(Och3)Ch3 is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity for demanding synthetic applications. Each lot is subjected to comprehensive analytical testing including HPLC, NMR, and mass spectrometry. A Certificate of Analysis (COA) detailing purity, identity, and specific impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. This material is hygroscopic (moisture-sensitive). Allow the sealed container to equilibrate to room temperature before opening to prevent condensation and moisture ingress. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.