Description

Seb Domain (144-153) is a synthetic peptide fragment derived from the sebaceous differentiation-associated protein. This compound is a critical research-grade biochemical tool for studying skin biology, sebaceous gland function, and related dermatological pathways. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and biotechnology companies focused on dermatology, cosmetics science, and inflammatory skin conditions.

Application

• Biomedical Research: Used as a key antigen or reference standard in immunological assays to study autoimmune responses and skin inflammation.
• Dermatology R&D: Fundamental tool for investigating the molecular mechanisms of sebaceous gland differentiation and associated diseases like acne vulgaris.
• Cosmetic Science: Employed in in vitro studies to evaluate the efficacy of active ingredients targeting sebum regulation and skin barrier function.
• Antibody Production: Serves as an immunogen for generating specific polyclonal or monoclonal antibodies for diagnostic and research applications.
• Peptide Mapping: Acts as a defined fragment in proteomic studies for the characterization of larger proteins within the sebaceous differentiation pathway.
• Drug Discovery: Used in high-throughput screening (HTS) platforms to identify potential modulators of sebaceous activity for therapeutic development.

Basic Information

Product Name	Seb Domain (144-153)
CAS No.	210229-94-0
Molecular Formula	C55H84N14O15
Molecular Weight	1133.3 g/mol
Synonyms	Sebaceous Differentiation-Associated Protein Fragment (144-153); Seb d 144-153; Seb-derived peptide (144-153); Human Seb Domain Peptide; SDA Fragment (144-153); H-Ser-Gln-Leu-Gln-Asp-Leu-Gln-Ser-Leu-Arg-OH; SQQLQDLQSLR; Seb autoantigen peptide.
EINECS	Contact for details

Quality Control

Every batch of Seb Domain (144-153) is manufactured under strict quality management systems and undergoes comprehensive analytical characterization to ensure identity, purity, and consistency. Our standard specification meets the rigorous demands of research and development. A detailed Certificate of Analysis (COA) providing results for purity (HPLC), molecular weight (MS), and peptide content is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dedicated freezer. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and hydrolysis. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Molecular Weight (MS)	1133.3 ± 1.0 Da
Peptide Content	≥ 70% (by weight)
Amino Acid Analysis	Within ± 10% of theoretical
Solubility	Soluble in water, dilute acetic acid

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.