Description

[2-(Trimethylammonium)Ethyl] Methanethiosulfonate Chloride is a specialized, high-purity chemical reagent primarily used as a sulfhydryl-reactive labeling and crosslinking agent. This compound is valued for its ability to introduce a permanent positive charge or a cleavable disulfide bond into biomolecules, enabling advanced research and development. It is essential for scientists and manufacturers in the fields of bioconjugation, protein chemistry, and proteomics, where precise molecular modification is critical.

Application

• Bioconjugation Reagent: For site-specific modification of cysteine residues in proteins and peptides.
• Crosslinking Agent: Used in the study of protein-protein interactions and complex structures.
• Mass Spectrometry Tags: Acts as a charge-tagging reagent to enhance ionization efficiency in MS-based proteomic analysis.
• Surface Functionalization: For modifying gold surfaces or nanoparticles via thiol-gold chemistry for biosensor development.
• Antibody-Drug Conjugate (ADC) Research: A key intermediate in the development of novel linker-payload systems.
• Enzyme Immobilization: Facilitates the covalent attachment of enzymes to solid supports while potentially modulating activity.

Basic Information

Product Name	[2-(Trimethylammonium)Ethyl] Methanethiosulfonate Chloride
CAS No.	210167-37-6
Molecular Formula	C6H16ClNO2S2
Molecular Weight	233.78 g/mol
Synonyms	MTSET; (2-Trimethylammoniumethyl) Methanethiosulfonate Chloride; MTSET Bromide Analog (Chloride Salt); [2-(Trimethylammonio)ethyl] Methanethiosulfonate Chloride; Ammonium, (2-((methylsulfonyl)thio)ethyl)trimethyl-, chloride; MTSEA+ Chloride; Thiol-reactive trimethylammonium reagent
EINECS	Contact for details

Quality Control

Our [2-(Trimethylammonium)Ethyl] Methanethiosulfonate Chloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles for production and quality management to support our global clientele in pharmaceutical and life science research.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a desiccated environment to prevent degradation. For long-term stability, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.