Description

2-Amino-3,4,7,8-Tetramethyl-3H-Imidazo[4,5-F]Quinoxaline 2-14C is a carbon-14 labeled derivative of a heterocyclic aromatic amine, a critical tool for advanced research requiring isotopic tracing. This compound is essential for conducting precise metabolic, pharmacokinetic, and environmental fate studies where tracking the molecule's pathway is paramount. It is primarily utilized by research institutions, pharmaceutical developers, and contract research organizations (CROs) engaged in toxicology, carcinogenicity research, and analytical method development.

Application

• Metabolic Pathway Tracing: Used as a radiolabeled tracer in ADME (Absorption, Distribution, Metabolism, and Excretion) studies to elucidate the biological fate of heterocyclic amines.
• Toxicology and Carcinogenicity Research: Serves as a key standard or reagent in investigating the formation, bioactivation, and DNA adduct formation of food-borne mutagens.
• Analytical Method Development: Acts as an internal standard or reference compound in advanced chromatographic (LC-MS, HPLC) and spectroscopic methods for quantifying trace amines.
• Pharmaceutical Research: Facilitates drug discovery and development processes where understanding the precise breakdown and distribution of compound analogs is required.
• Environmental Fate Studies: Employed to study the degradation, transformation, and persistence of similar aromatic amine structures in various ecosystems.
• Biochemical Mechanism Elucidation: Aids in research focused on enzyme-substrate interactions and the metabolic activation pathways of nitrogen-containing heterocycles.

Basic Information

Product Name	2-Amino-3,4,7,8-Tetramethyl-3H-Imidazo[4,5-F]Quinoxaline 2-14C
CAS No.	210049-21-1
Molecular Formula	C₁₃¹⁴CH₁₆N₆
Molecular Weight	Contact for details
Synonyms	2-Amino-3,4,7,8-tetramethylimidazo[4,5-f]quinoxaline-2-14C; 2-14C-MeIQx; [2-14C]-2-Amino-3,4,7,8-tetramethyl-3H-imidazo[4,5-f]quinoxaline; Carbon-14 Labeled MeIQx; Radiolabeled 2-Amino-3,4,7,8-tetramethylimidazoquinoxaline; 14C-MeIQx; 2-14C-3,4,7,8-Tetramethylimidazo[4,5-f]quinoxalin-2-amine
EINECS	Contact for details

Quality Control

Every batch of our carbon-14 labeled compounds is manufactured and handled under strict quality systems to ensure isotopic purity, chemical purity, and radiochemical stability. We provide comprehensive Certificates of Analysis (COA) detailing specific activity, radiochemical purity (typically >97% by HPLC), chemical purity, and solvent content. Our production adheres to cGMP principles where applicable, supporting regulatory submissions for non-clinical research.

Storage

Preserve in a tightly closed container, protected from light. Store at recommended temperatures (typically 2-8°C or as specified on the label) in a designated, secure area for radioactive materials. Follow all local and international regulations for the storage and handling of radiochemicals.

Specification

Item	Specification
Appearance	Solid (Color to be specified per batch)
Identification (IR/HPLC)	Conforms to reference standard
Specific Activity	Contact for details (mCi/mmol)
Radiochemical Purity (HPLC)	≥ 97%
Chemical Purity (HPLC)	≥ 95%
Solvent Content (Residual Solvents)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.