Description

2,4,6-Trifluorophenylacetic Acid is a versatile fluorinated aromatic building block of significant importance in modern synthetic chemistry. Its value lies in the unique electronic and steric properties imparted by the trifluoromethyl-substituted phenyl ring, making it a critical intermediate for the development of advanced materials and active pharmaceutical ingredients (APIs). This compound is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides, where the fluorine atoms enhance biological activity and environmental stability.
• Liquid Crystal Materials: Serves as a precursor for fluorinated liquid crystal compounds used in high-performance displays.
• Polymer Chemistry: Incorporated as a monomer or modifier to create specialty polymers with improved thermal stability and chemical resistance.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, such as Suzuki or Heck reactions, to introduce the trifluorophenylacetic acid moiety into complex molecules.
• Chemical Research & Development: Utilized in academic and industrial R&D for exploring new synthetic methodologies and creating compound libraries.

Basic Information

Product Name	2,4,6-Trifluorophenylacetic Acid
CAS No.	209991-63-9
Molecular Formula	C8H5F3O2
Molecular Weight	198.12 g/mol
Synonyms	(2,4,6-Trifluorophenyl)acetic Acid; 2-(2,4,6-Trifluorophenyl)acetic Acid; α-(2,4,6-Trifluorophenyl)acetic Acid; 2,4,6-Trifluorobenzeneacetic Acid; TFPAA; 209991-63-9; NSC 405124
EINECS	Contact for details

Quality Control

Our 2,4,6-Trifluorophenylacetic Acid is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements of our global clientele in advanced research and manufacturing. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.