Description

(11Br)-N,n-Bis[(S)-1-Phenylethyl]-Dinaphtho[2,1-D:1',2'-F][1,3,2]Dioxaphosphepin-4-Amine is a sophisticated chiral organophosphorus compound featuring a unique dinaphthodioxaphosphepin core. This compound is valued as a high-performance ligand or catalyst precursor in asymmetric synthesis, enabling the production of enantiomerically pure pharmaceuticals and fine chemicals. It is primarily utilized by research institutions and industrial R&D departments focused on advanced organic synthesis, particularly in the pharmaceutical and agrochemical sectors.

Application

• Asymmetric Catalysis: Serving as a chiral ligand for transition metal-catalyzed reactions such as hydrogenation, hydroformylation, and cross-coupling.
• Pharmaceutical Intermediate Synthesis: Facilitating the enantioselective construction of complex molecular architectures for active pharmaceutical ingredients (APIs).
• Agrochemical Research: Used in the development of chiral pesticides and herbicides with improved efficacy and environmental profiles.
• Material Science: Potential application in the synthesis of chiral polymers or advanced functional materials.
• Academic & Industrial R&D: A key reagent for methodological development in organic chemistry and process optimization.

Basic Information

Product Name	(11Br)-N,n-Bis[(S)-1-Phenylethyl]-Dinaphtho[2,1-D:1',2'-F][1,3,2]Dioxaphosphepin-4-Amine
CAS No.	209482-28-0
Molecular Formula	C₃₉H₃₃BrNO₂P
Molecular Weight	658.56 g/mol
Synonyms	(11bR)-N,N-Bis[(1S)-1-Phenylethyl]dinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin-4-amine; (R)-DTBM-SEGPHOS; (R)-3,3'-Bis[di(1S)-1-phenylethylamino]-5,5',6,6',7,7',8,8'-octahydro-1,1'-binaphthyl-2,2'-diyl hydrogenphosphate; (R)-DTBM-SEGPHOS ligand; DTBM-SEGPHOS (R); SEGPHOS derivative; Chiral phosphoramidite ligand.
EINECS	Contact for details

Quality Control

Our production of (11Br)-N,n-Bis[(S)-1-Phenylethyl]-Dinaphtho[2,1-D:1',2'-F][1,3,2]Dioxaphosphepin-4-Amine adheres to stringent quality protocols to ensure batch-to-batch consistency and high chiral purity. Each lot is characterized by advanced analytical techniques including HPLC, NMR, and chiral analysis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and enantiomeric excess is provided with every shipment, supporting cGMP and ISO quality management principles for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). For long-term storage under inert atmosphere (argon or nitrogen) is recommended to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.