Description

S-(3,5-Dioxa-4-Phospha-Cyclohepta[2,1-A:3,4-A']Dinaphthalen-4-Yl)Bis[(1S)-1-Phenylethyl]Amine is a sophisticated chiral phosphine-amine hybrid ligand, a key building block in advanced asymmetric catalysis. Its value lies in enabling highly selective and efficient transition metal-catalyzed reactions, crucial for producing enantiomerically pure intermediates. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries who require precise stereochemical control in complex synthesis.

Application

• Asymmetric Hydrogenation: A key ligand for the enantioselective reduction of prochiral olefins, ketones, and imines to produce chiral alcohols and amines.
• Pharmaceutical Intermediate Synthesis: Used in the catalytic synthesis of enantiomerically pure active pharmaceutical ingredients (APIs) and key chiral building blocks.
• Cross-Coupling Reactions: Facilitates asymmetric versions of Suzuki, Heck, and other C-C bond-forming reactions with high stereoselectivity.
• Agrochemical Production: Employed in the development of chiral herbicides, fungicides, and plant growth regulators.
• Academic & Industrial R&D: A valuable tool for methodology development in organic synthesis and catalysis research.
• Fine Chemical Manufacturing: For the production of specialty flavors, fragrances, and advanced materials requiring specific chirality.

Basic Information

Product Name	S-(3,5-Dioxa-4-Phospha-Cyclohepta[2,1-A:3,4-A']Dinaphthalen-4-Yl)Bis[(1S)-1-Phenylethyl]Amine
CAS No.	209482-27-9
Molecular Formula	C37H32NO2P
Molecular Weight	553.63 g/mol
Synonyms	(S)-BINAPHANE; (S)-2,2'-Bis[(R)-1-(diphenylphosphino)ethyl]-1,1'-binaphthyl; (S)-Bis[(R)-1-(diphenylphosphino)ethyl]-1,1'-binaphthyl-2,2'-diyl ether; (S)-Bis[(R)-1-(diphenylphosphino)ethyl]-2,2'-bis(1,1'-binaphthyl) ether; BINAPHANE ligand; (S,S)-BINAPHANE; (S)-BINAPHANE ligand; (S)-2,2'-Bis[(R)-1-(diphenylphosphino)ethyl]-1,1'-binaphthyl-2,2'-diyl ether
EINECS	Contact for details

Quality Control

Our S-(3,5-Dioxa-4-Phospha-Cyclohepta[2,1-A:3,4-A']Dinaphthalen-4-Yl)Bis[(1S)-1-Phenylethyl]Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure high chemical and enantiomeric purity suitable for sensitive catalytic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term storage, keep the container under an inert atmosphere (argon or nitrogen) at a controlled room temperature (15-25°C). This compound is easily oxidized and moisture-sensitive; ensure the container is sealed immediately after use to maintain stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.