Description

Fmoc-(S)-3-Amino-3-Phenylpropionic Acid CAS NO 209252-15-3 is a high-purity, chiral amino acid derivative featuring an Fmoc-protected amine group and a carboxylic acid functionality. This compound is a critical building block in solid-phase peptide synthesis (SPPS), enabling the controlled introduction of non-proteinogenic amino acid residues into peptide chains. It is essential for researchers and manufacturers in pharmaceutical development, biotechnology, and advanced materials science who require reliable, high-quality intermediates for creating complex peptides and peptidomimetics.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key protected amino acid building block for the automated synthesis of therapeutic and research peptides.
• Pharmaceutical Intermediates: Used in the research and development of novel peptide-based drugs and active pharmaceutical ingredients (APIs).
• Bioconjugation: Serves as a linker or spacer molecule for attaching peptides to other biomolecules, surfaces, or polymers.
• Combinatorial Chemistry: Employed in libraries for drug discovery to create diverse arrays of peptide-like compounds.
• Academic & Industrial Research: Fundamental reagent for studying peptide structure-activity relationships and developing new synthetic methodologies.

Basic Information

Product Name	Fmoc-(S)-3-Amino-3-Phenylpropionic Acid
CAS No.	209252-15-3
Molecular Formula	C24H21NO4
Molecular Weight	387.43 g/mol
Synonyms	Fmoc-β3-hPhe-OH; Fmoc-(S)-3-Amino-3-(phenyl)propanoic Acid; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-3-amino-3-phenylpropionic Acid; (S)-3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-phenylpropanoic Acid; Fmoc-3-Amino-3-phenylpropionic Acid; Fmoc-DL-3-Amino-3-phenylpropionic Acid (related); N-Fmoc-3-amino-3-phenylpropionic acid
EINECS	Contact for details

Quality Control

Our Fmoc-(S)-3-Amino-3-Phenylpropionic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets the high standards required for peptide synthesis. Certificates of Analysis (COA) detailing identity, purity, and specific test results are available for every lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0%
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.