Description

3-Chloro-5-Methoxypicolinonitrile is a versatile pyridine-based nitrile derivative, serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring both chloro and methoxy substituents, makes it a valuable intermediate for constructing complex pharmacophores and functional materials. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its heterocyclic core for bioactivity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in metal-catalyzed cross-coupling reactions.
• Material Science Research: Employed in the synthesis of organic electronic materials and liquid crystals due to its electron-withdrawing nitrile group and aromatic system.
• Custom Synthesis and Contract Manufacturing: A high-demand intermediate for custom chemical synthesis services catering to R&D and pilot-scale production.

Basic Information

Product Name	3-Chloro-5-Methoxypicolinonitrile
CAS No.	208994-06-3
Molecular Formula	C7H5ClN2O
Molecular Weight	168.58 g/mol
Synonyms	3-Chloro-5-methoxypyridine-2-carbonitrile; 2-Cyano-3-chloro-5-methoxypyridine; 5-Methoxy-3-chloropicolinonitrile; 3-Chloro-5-methoxy-2-pyridinecarbonitrile; 208994-06-3; 3-Chloro-5-methoxypicolinonitrile; 3-Chloro-5-methoxy-2-cyanopyridine
EINECS	Contact for details

Quality Control

Every batch of 3-Chloro-5-Methoxypicolinonitrile is manufactured under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the high-purity standards required for research and scale-up activities. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.