Description

4-Cyano-n-(3-Ethynylphenyl)Benzene-1-Sulfonamide is a specialized sulfonamide derivative featuring both cyano and ethynyl functional groups, making it a valuable synthetic intermediate for advanced organic chemistry. This compound is critical for researchers and manufacturers developing novel pharmaceuticals and functional materials, particularly in kinase inhibitor research and targeted drug discovery. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material sectors seeking to incorporate its unique molecular scaffold into new active compounds.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of kinase inhibitors and other targeted therapeutic agents.
• Chemical Biology Probe: Used in medicinal chemistry for structure-activity relationship (SAR) studies and hit-to-lead optimization.
• Organic Synthesis: Serves as a versatile precursor for further functionalization via click chemistry (using the ethynyl group) and other cross-coupling reactions.
• Material Science Research: Potential monomer or precursor for developing specialty polymers and advanced organic electronic materials.
• Agrochemical Development: Intermediate in the research and synthesis of novel crop protection agents and herbicides.

Basic Information

Product Name	4-Cyano-n-(3-Ethynylphenyl)Benzene-1-Sulfonamide
CAS No.	208943-22-0
Molecular Formula	C15H10N2O2S
Molecular Weight	282.32 g/mol
Synonyms	4-Cyano-N-(3-ethynylphenyl)benzenesulfonamide; N-(3-Ethynylphenyl)-4-cyanobenzenesulfonamide; Benzenesulfonamide, 4-cyano-N-(3-ethynylphenyl)-; 4-CN-N-(3-EP)BSA; 208943-22-0; 4-Cyano-N-(3-ethynylphenyl)benzene-1-sulfonamide
EINECS	Contact for details

Quality Control

Our 4-Cyano-n-(3-Ethynylphenyl)Benzene-1-Sulfonamide is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide Certificates of Analysis (COA) with detailed specifications for traceability and quality assurance, supporting cGMP-compliant research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.