Description

Iso Rizatriptan CAS NO 208941-96-2 is a high-purity chemical compound, specifically an isomer of the active pharmaceutical ingredient Rizatriptan. This material is critical for pharmaceutical research and development, particularly in the study of drug metabolism, impurity profiling, and the synthesis of novel therapeutic agents. It serves as a key reference standard and intermediate for analytical laboratories and R&D departments within the global pharmaceutical and fine chemical industries.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for the identification and quantification of impurities in Rizatriptan Benzoate active pharmaceutical ingredient (API) and finished dosage forms.
• Analytical Research: Essential for method development and validation in HPLC, LC-MS, and other chromatographic techniques within quality control (QC) and analytical R&D laboratories.
• Process Chemistry & Impurity Synthesis: Employed as a building block or intermediate in the synthesis of related compounds and for studying metabolic pathways.
• Regulatory Compliance & Documentation: Supports regulatory filings (e.g., for FDA, EMA) by providing well-characterized impurity samples for stability studies and safety assessments.
• Academic & Contract Research: Utilized in universities and CROs (Contract Research Organizations) for pharmacological studies and investigative research on migraine therapeutics.

Basic Information

Product Name	Iso Rizatriptan
CAS No.	208941-96-2
Molecular Formula	C15H19N5
Molecular Weight	269.35 g/mol
Synonyms	Rizatriptan Impurity; Rizatriptan Related Compound; 3-[2-(Dimethylamino)ethyl]-5-(1H-1,2,4-triazol-1-ylmethyl)-1H-indole; MK-0462 Isomer; N,N-Dimethyl-2-[5-(1H-1,2,4-triazol-1-ylmethyl)-1H-indol-3-yl]ethan-1-amine; Rizatriptan Isomer; 5-[(1H-1,2,4-Triazol-1-yl)methyl]-1H-indole-3-ethanamine, N,N-dimethyl-
EINECS	Contact for details

Quality Control

Our Iso Rizatriptan is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and stringent control of residual solvents and heavy metals. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with relevant pharmacopeial guidelines for reference standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 1.0% w/w
Assay (on dried basis)	97.0% - 103.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.