Description

Bexxar CAS NO 208921-02-2 is a specialized pharmaceutical compound, specifically a radiolabeled monoclonal antibody conjugate. This product is critical for targeted radiotherapy, offering a precise mechanism of action for treating specific hematologic malignancies. It is primarily utilized by pharmaceutical manufacturers, advanced research institutions, and specialized healthcare providers in oncology and nuclear medicine.

Application

• Targeted Radiotherapy Agent: Primary use in the treatment of relapsed or refractory, CD20-positive, follicular non-Hodgkin's lymphoma (NHL).
• Pharmaceutical Active Ingredient: Serves as the key active component in the formulation of finished radiopharmaceutical drugs.
• Oncology Research: Used in preclinical and clinical research to study radioimmunotherapy mechanisms and develop next-generation targeted cancer therapies.
• Nuclear Medicine: Employed in specialized medical centers for the preparation of patient-specific therapeutic doses.
• Bioconjugation Studies: Acts as a reference standard in R&D for developing novel antibody-radionuclide conjugates.

Basic Information

Product Name	Bexxar
CAS No.	208921-02-2
Molecular Formula	C6480H10004N1736O2016S44
Molecular Weight	Approx. 145 kDa
Synonyms	Tositumomab and Iodine I 131 Tositumomab; Anti-CD20 Monoclonal Antibody-I-131 Conjugate; Iodine-131 Tositumomab; 131I-Tositumomab; Bexxar Therapeutic Regimen; Tositumomab-Iodine131; NSC-710074
EINECS	Contact for details

Quality Control

Our Bexxar is manufactured under strict quality systems. Each batch is subjected to a comprehensive suite of analytical tests to ensure identity, purity, potency, and radiochemical purity. We provide full traceability and Certificates of Analysis (COA) are available upon request, detailing compliance with relevant pharmacopeial and regulatory guidelines for radiopharmaceuticals.

Storage

Preserve in a tightly closed container, protected from light. Store at the temperature specified on the label, typically under controlled cold conditions (2-8°C). Due to its hygroscopic (moisture-sensitive) nature, protect from humidity. Handle and store in accordance with all applicable radiation safety regulations.

Specification

Item	Specification
Appearance	Clear, colorless to slightly yellow solution
Identification (HPLC/Immunoassay)	Conforms to reference standard
Assay (Radioactivity)	90.0% - 110.0% of labeled amount
Radiochemical Purity (HPLC/TLC)	≥ 95.0%
Immunoreactive Fraction	≥ 80.0%
Protein Concentration	Within specified range
pH	6.5 - 7.5
Sterility Test	Sterile
Bacterial Endotoxins	< 5.0 EU/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.