Description

n-[(3S,4R,5R,6R)-4,5-Bis(Phenylmethoxy)-6-[(Phenylmethoxy)Methyl]-3-Piperidinyl]Acetamide is a high-purity, complex chiral piperidine derivative, serving as a critical advanced intermediate in modern organic synthesis. Its value lies in its precise stereochemistry and functional groups, which are essential for constructing sophisticated molecular architectures. This compound is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers engaged in developing novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex glycosidase inhibitors or neuraminidase-related compounds.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of complex drug candidates, especially those targeting viral enzymes or metabolic pathways.
• Glycosidase Inhibitor Research: Serves as a core structural motif in the development and study of potent glycosidase inhibitors for therapeutic applications.
• Neuraminidase Inhibitor Synthesis: Used in research-scale production of neuraminidase inhibitor analogs, relevant to antiviral drug discovery.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes to study carbohydrate-processing enzymes and their biological functions.
• Asymmetric Synthesis: Utilized as a chiral auxiliary or template in stereoselective synthesis to induce specific stereochemistry in target molecules.
• Process Chemistry Development: Acts as a model compound for scaling up and optimizing complex multi-step synthetic routes under cGMP conditions.

Basic Information

Product Name	n-[(3S,4R,5R,6R)-4,5-Bis(Phenylmethoxy)-6-[(Phenylmethoxy)Methyl]-3-Piperidinyl]Acetamide
CAS No.	208592-92-1
Molecular Formula	C29H35NO5
Molecular Weight	477.60 g/mol
Synonyms	1,2,3,4-Tetra-O-benzyl-D-erythro-L-galacto-octitol; (3S,4R,5R,6R)-4,5-Bis(benzyloxy)-6-[(benzyloxy)methyl]-1-(2-oxoethyl)piperidin-3-amine derivative; N-Acetyl-1,2,3,4-tetra-O-benzyl-D-erythro-L-galacto-octitol-1,5-imine; Tetra-O-benzyl-D-erythro-L-galacto-octitol amine acetate; CAS 208592-92-1; Advanced Neuraminidase Inhibitor Intermediate; Chiral Piperidine Acetamide Derivative
EINECS	Contact for details

Quality Control

Our n-[(3S,4R,5R,6R)-4,5-Bis(Phenylmethoxy)-6-[(Phenylmethoxy)Methyl]-3-Piperidinyl]Acetamide is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to ICH Q7 guidelines for active pharmaceutical ingredients (APIs) and can support customer audits and regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Specific Rotation	[α]20/D: Contact for details
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.