Description

D-Alanine, n-(Methoxycarbonyl)-, Methyl Ester (9Ci) is a chiral, protected amino acid derivative of significant interest in advanced organic synthesis. This high-purity building block is critical for researchers and manufacturers requiring precise stereochemistry and functional group compatibility. It is primarily utilized in the development of pharmaceuticals, peptide-based therapeutics, and specialized agrochemicals where the D-configuration of alanine is essential for biological activity or metabolic stability.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of novel active pharmaceutical ingredients (APIs), particularly antibiotics and enzyme inhibitors.
• Peptide Synthesis: Serves as a protected D-alanine derivative for the solid-phase and solution-phase synthesis of non-natural and therapeutic peptides.
• Agrochemical Research: Used in the development of chiral pesticides and herbicides where specific stereochemistry influences efficacy and environmental degradation.
• Biochemical Research: Employed as a substrate or inhibitor in enzymatic studies and for probing biological mechanisms.
• Material Science: A potential monomer or modifier for creating specialized polymers with unique chiral properties.

Basic Information

Product Name	D-Alanine, n-(Methoxycarbonyl)-, Methyl Ester (9Ci)
CAS No.	208453-80-9
Molecular Formula	C6H11NO4
Molecular Weight	161.16 g/mol
Synonyms	Methyl N-(methoxycarbonyl)-D-alaninate; D-Alanine, N-carboxy-, methyl ester, N-methyl ester; (R)-Methyl 2-((methoxycarbonyl)amino)propanoate; Methyl (R)-2-((methoxycarbonyl)amino)propanoate; N-Carbomethoxy-D-alanine methyl ester; D-N-Carbomethoxyalanine methyl ester; Methyl N-methoxycarbonyl-D-alaninate
EINECS	Contact for details

Quality Control

Our D-Alanine, n-(Methoxycarbonyl)-, Methyl Ester (9Ci) is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and cGMP manufacturing. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and other critical specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee (D-isomer)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.