Description

Ethyl-2,2-Difluoro-2-(3,5-Difluorophenyl)Acetate is a high-value fluorinated organic building block, essential for introducing a difluorophenylacetate moiety into complex molecular architectures. Its primary commercial value lies in serving as a key intermediate in the synthesis of advanced pharmaceutical compounds, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. This product is critical for R&D and production teams in the pharmaceutical, agrochemical, and specialty chemical industries seeking to incorporate specific fluorine-substituted phenyl groups.

Application

• Pharmaceutical Intermediate: A crucial building block for synthesizing novel drug candidates, especially in therapeutic areas like oncology and central nervous system (CNS) disorders.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the difluorophenyl group enhances biological activity and stability.
• Material Science Research: Serves as a monomer or precursor for developing specialty polymers and advanced materials with unique properties.
• Ligand and Catalyst Development: Employed in organic chemistry research to create novel ligands and catalysts for asymmetric synthesis and other catalytic processes.
• Fluorine Chemistry Studies: An important reagent for academic and industrial research focused on the synthesis and reactivity of organofluorine compounds.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules.

Basic Information

Product Name	Ethyl-2,2-Difluoro-2-(3,5-Difluorophenyl)Acetate
CAS No.	208259-49-8
Molecular Formula	C10H8F4O2
Molecular Weight	236.16 g/mol
Synonyms	Ethyl 2,2-Difluoro-2-(3,5-difluorophenyl)acetate; 2-(3,5-Difluorophenyl)-2,2-difluoroacetic Acid Ethyl Ester; Acetic acid, 2,2-difluoro-2-(3,5-difluorophenyl)-, ethyl ester; Ethyl α,α-Difluoro-3,5-difluorophenylacetate; 3,5-Difluoro-α,α-difluorobenzeneacetic Acid Ethyl Ester; Ethyl (3,5-Difluorophenyl)difluoroacetate; DFPA Ethyl Ester
EINECS	Contact for details

Quality Control

Our Ethyl-2,2-Difluoro-2-(3,5-Difluorophenyl)Acetate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment ensures the material meets the stringent requirements for use as a pharmaceutical intermediate.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (by GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.