Description

2,6-Difluoromandelic Acid is a high-value fluorinated mandelic acid derivative, serving as a critical chiral building block and synthetic intermediate. Its significance lies in the unique reactivity imparted by the fluorine atoms at the 2- and 6-positions, which are strategically valuable for modulating the biological activity and physicochemical properties of target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of novel active ingredients and complex organic frameworks.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for drugs targeting the central nervous system and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the development of advanced herbicides and pesticides, where the fluorine atoms enhance lipophilicity and metabolic stability.
• Ligand and Catalyst Development: Employed in the preparation of chiral ligands for asymmetric catalysis, facilitating enantioselective synthesis.
• Material Science Research: Acts as a monomer or modifier in the creation of specialty polymers with tailored properties.
• Chemical Biology Probes: Utilized for synthesizing fluorinated analogs of natural products to study biochemical pathways and enzyme mechanisms.
• Academic & Contract Research: Serves as a versatile starting material for methodological development and novel compound library synthesis in R&D laboratories.

Basic Information

Product Name	2,6-Difluoromandelic Acid
CAS No.	207981-50-8
Molecular Formula	C8H6F2O3
Molecular Weight	188.13 g/mol
Synonyms	2,6-Difluoromandelic Acid; (2,6-Difluorophenyl)(hydroxy)acetic acid; α-Hydroxy-2,6-difluorophenylacetic acid; DL-2,6-Difluoromandelic Acid; (±)-2,6-Difluoromandelic Acid; 2,6-Difluorobenzene glycolic acid; Mandelic acid, 2,6-difluoro-
EINECS	Contact for details

Quality Control

Our 2,6-Difluoromandelic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request, providing full traceability and compliance support for your regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The product may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	Racemic mixture (DL-Form)
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.