Description

2-Fluoro-5-(trifluoromethyl)benzamide is a high-value fluorinated aromatic building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both fluorine and trifluoromethyl substituents, is engineered to modulate the physicochemical properties of target molecules, enhancing metabolic stability and lipophilicity. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for kinase inhibitors and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Used in the design and production of advanced herbicides and pesticides, where the fluorine atoms contribute to biological activity and environmental persistence.
• Material Science Precursor: Serves as a starting material for synthesizing specialty polymers, liquid crystals, and organic electronic materials requiring fluorinated aromatic units.
• Chemical Research: Employed in academic and industrial laboratories for method development in cross-coupling reactions and fluorination chemistry.
• Custom Synthesis & Contract Manufacturing: A critical building block for custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	2-Fluoro-5-(trifluoromethyl)benzamide
CAS No.	207919-05-9
Molecular Formula	C8H5F4NO
Molecular Weight	207.12 g/mol
Synonyms	2-Fluoro-5-(trifluoromethyl)benzamide; 2-Fluoro-alpha,alpha,α-trifluoro-m-toluamide; 5-(Trifluoromethyl)-2-fluorobenzamide; Benzamide, 2-fluoro-5-(trifluoromethyl)-; m-(Trifluoromethyl)-2-fluorobenzamide; 2-Fluoro-5-trifluoromethylbenzamide; 2-Fluoro-α,α,α-trifluoro-m-toluamide
EINECS	Contact for details

Quality Control

Every batch of 2-Fluoro-5-(trifluoromethyl)benzamide is manufactured under strict quality management protocols. We provide comprehensive analytical documentation to ensure traceability and consistency for your critical R&D and production processes. A detailed Certificate of Analysis (COA) confirming identity, purity (typically ≥97% by HPLC), and impurity profile is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.