Description

2-Bromo-3,5-Dimethoxy-1-Fluorobenzene is a high-purity fluorinated aromatic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily needed by R&D chemists and process development scientists for constructing active pharmaceutical ingredients (APIs), liquid crystal materials, and functionalized ligands.

Application

• Pharmaceutical Intermediate: A versatile building block for the synthesis of novel drug candidates, especially those requiring fluorinated aromatic cores for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the bromo and fluoro substituents allow for precise structural modifications.
• Material Science: Serves as a precursor for functionalized monomers and ligands used in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck, Sonogashira) to create complex biaryl structures.
• Chemical Research & Development: Employed in academic and industrial labs for methodological studies in fluorination chemistry and the exploration of new reaction pathways.

Basic Information

Product Name	2-Bromo-3,5-Dimethoxy-1-Fluorobenzene
CAS No.	206860-47-1
Molecular Formula	C8H8BrFO2
Molecular Weight	235.05 g/mol
Synonyms	1-Bromo-2-fluoro-3,5-dimethoxybenzene; 2-Fluoro-3,5-dimethoxybromobenzene; Benzene, 2-bromo-3,5-dimethoxy-1-fluoro-; 3,5-Dimethoxy-2-fluorobromobenzene; 2-Bromo-3,5-dimethoxyfluorobenzene; 1-Fluoro-2-bromo-3,5-dimethoxybenzene; 3,5-Dimethoxy-1-fluoro-2-bromobenzene
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-3,5-Dimethoxy-1-Fluorobenzene is manufactured and tested under a strict quality management system. We guarantee high chemical purity and consistency, supported by comprehensive analytical documentation. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to ensure it meets your specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.