Description

Benzamidine Hydrochloride Hydrate is a potent and selective competitive inhibitor of serine proteases, including trypsin and trypsin-like enzymes. This compound is a critical biochemical tool and pharmaceutical intermediate, valued for its high purity and consistent performance in research and manufacturing. It is essential for scientists and manufacturers in the pharmaceutical, biotechnology, and life science research sectors, particularly in enzyme kinetics studies, proteomics, and the development of therapeutic agents.

Application

• Biochemical Research: A fundamental reagent for studying serine protease mechanisms, enzyme inhibition kinetics, and protein-protein interactions.
• Pharmaceutical Intermediates: Serves as a key building block in the synthesis of more complex protease inhibitors and potential therapeutic compounds.
• Proteomics & Cell Biology: Used to inhibit specific proteases in cell lysates and biological samples to prevent protein degradation during analysis.
• Diagnostic Reagent Manufacturing: Incorporated into diagnostic kits and assays that utilize or detect trypsin-like enzyme activity.
• Academic & Industrial R&D: A staple chemical in laboratories for fundamental life science research and drug discovery programs.

Basic Information

Product Name	Benzamidine Hydrochloride Hydrate
CAS No.	206752-36-5
Molecular Formula	C7H8N2•HCl•xH2O
Molecular Weight	156.61 (anhydrous basis)
Synonyms	Benzamidine HCl Hydrate; Benzenecarboximidamide Hydrochloride Hydrate; Benzamidinium Chloride Hydrate; Benzamidine Monohydrochloride Hydrate; NSC 759; 4-Amidinobenzylamine Hydrochloride (related); Trypsin Inhibitor (Benzamidine); BZH
EINECS	Contact for details

Quality Control

Our Benzamidine Hydrochloride Hydrate is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with the standards expected for research and pharmaceutical-grade intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent absorption of atmospheric moisture, which can affect stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm
Solubility (in water)	Clear, colorless solution

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.