Description

3-(n-Boc)Amino-3-(2-Nitro-Phenyl)-Propionic Acid is a high-purity, protected amino acid derivative that serves as a critical building block in advanced organic synthesis. This compound is essential for researchers and manufacturers requiring precise molecular architecture, particularly in the development of complex, nitrogen-containing target molecules. It is primarily utilized by pharmaceutical R&D teams and fine chemical producers engaged in peptide mimetic design, medicinal chemistry, and the synthesis of novel active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates, particularly for protease inhibitors and other targeted therapies.
• Peptidomimetics Synthesis: Used to incorporate non-natural amino acid residues into peptide chains to enhance stability, bioavailability, and biological activity.
• Medicinal Chemistry & SAR Studies: Enables the systematic exploration of structure-activity relationships by providing a versatile scaffold for chemical modification.
• Custom Chemical Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for the custom synthesis of complex organic molecules on a laboratory to pilot scale.
• Academic Research: Serves as a valuable reagent in university and institutional labs for methodology development and the synthesis of novel chemical entities.
• Protecting Group Strategy: The tert-butoxycarbonyl (Boc) group allows for orthogonal protection schemes in multi-step synthetic sequences, crucial for complex molecule assembly.

Basic Information

Product Name	3-(n-Boc)Amino-3-(2-Nitro-Phenyl)-Propionic Acid
CAS No.	206537-28-2
Molecular Formula	C14H18N2O6
Molecular Weight	310.30 g/mol
Synonyms	3-[(tert-Butoxycarbonyl)amino]-3-(2-nitrophenyl)propanoic acid; Boc-3-amino-3-(2-nitrophenyl)propionic acid; (R/S)-3-(Boc-amino)-3-(2-nitrophenyl)propionic acid; 3-(Boc-amino)-3-(o-nitrophenyl)propanoic acid; 2-Nitro-β-[(tert-butoxycarbonyl)amino]benzenepropanoic Acid; tert-Butyl [1-(2-nitrophenyl)-2-carboxyethyl]carbamate; 206537-28-2 (CAS)
EINECS	Contact for details

Quality Control

Our 3-(n-Boc)Amino-3-(2-Nitro-Phenyl)-Propionic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and pharmaceutical intermediate applications. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.