Description

L-Valine, n-[(1S)-1-Methyl-2-(Methylamino)-2-Oxo-1-Phenylethyl]-, Methyl Ester (9Ci) is a specialized, high-purity chiral building block and intermediate of significant interest in advanced organic synthesis. This compound is valued for its defined stereochemistry and functional groups, which enable precise molecular construction. It is primarily utilized by research institutions and pharmaceutical development teams engaged in the synthesis of complex molecules, including potential active pharmaceutical ingredients (APIs) and novel chemical entities.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral synthon in the research and development of new therapeutic agents and active pharmaceutical ingredients (APIs).
• Peptide & Peptidomimetic Synthesis: Used as a modified amino acid derivative for constructing peptide analogs and peptidomimetics with enhanced stability or biological activity.
• Asymmetric Synthesis: Acts as a key starting material or auxiliary in stereoselective synthesis to introduce specific chiral centers into target molecules.
• Medicinal Chemistry Research: Employed in lead optimization and structure-activity relationship (SAR) studies to explore new chemical spaces for drug discovery.
• Bioconjugation & Probe Development: Useful for creating labeled compounds or conjugates for biochemical and diagnostic research applications.
• Academic & Industrial R&D: Supports innovative synthetic methodology development in university laboratories and corporate R&D centers.

Basic Information

Product Name	L-Valine, n-[(1S)-1-Methyl-2-(Methylamino)-2-Oxo-1-Phenylethyl]-, Methyl Ester (9Ci)
CAS No.	206069-14-9
Molecular Formula	C16H24N2O3
Molecular Weight	292.38 g/mol
Synonyms	L-Valine, N-[(1S)-1-methyl-2-(methylamino)-2-oxo-1-phenylethyl]-, methyl ester; Methyl (2S)-2-[[(2S)-2-methyl-1-oxo-1-(phenyl)propan-2-yl](methyl)amino]-3-methylbutanoate; (S)-Methyl 2-((S)-2-methyl-1-oxo-1-phenylpropan-2-yl)(methyl)amino)-3-methylbutanoate; Valine derivative CAS 206069-14-9; N-[(1S)-1-Methyl-2-(methylamino)-2-oxo-1-phenylethyl]-L-valine methyl ester; A chiral valine methyl ester derivative
EINECS	Contact for details

Quality Control

Our L-Valine, n-[(1S)-1-Methyl-2-(Methylamino)-2-Oxo-1-Phenylethyl]-, Methyl Ester (9Ci) is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and high purity, suitable for research and development applications. We provide comprehensive analytical data, including HPLC purity, chiral purity, and structural confirmation. A detailed Certificate of Analysis (COA) is supplied with each batch, documenting compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.