Description

C18(Plasm)-22:6 Pe is a specialized phospholipid derivative, specifically a plasmalogen form of a phosphatidylethanolamine containing a C18 alkyl chain and docosahexaenoic acid (DHA, 22:6). This unique molecular structure is critical for advanced research into membrane biophysics, lipid signaling, and neurological health. It is an essential high-purity standard and building block for researchers and formulators in the pharmaceutical, nutraceutical, and life science industries.

Application

• Biomedical Research Standard: Used as a certified reference material for the analysis of plasmalogens and complex lipids in biological samples via LC-MS, GC-MS, and NMR.
• Lipidomics & Metabolomics: A critical internal standard for the quantitative profiling of phosphatidylethanolamine species and plasmalogen content in tissues, plasma, and cell cultures.
• Neurobiology Studies: Investigated for its role in neuronal membrane fluidity, anti-oxidative properties, and potential implications in neurodegenerative conditions.
• Pharmaceutical Development: Serves as a key intermediate or active component in the formulation of advanced drug delivery systems, particularly liposomes and lipid nanoparticles (LNPs).
• Nutraceutical R&D: Explored as a high-value ingredient in premium dietary supplements targeting cognitive function and cellular health due to its DHA and plasmalogen content.
• Cell Culture & Biochemistry: Utilized to study lipid raft dynamics, membrane protein function, and cellular signaling pathways in model systems.

Basic Information

Product Name	C18(Plasm)-22:6 Pe
CAS No.	206059-98-5
Molecular Formula	C45H78NO8P
Molecular Weight	792.07 g/mol
Synonyms	1-O-(1Z-Octadecenyl)-2-docosahexaenoyl-sn-glycero-3-phosphoethanolamine; (Plasm)-18:0-22:6 PE; 1-(1Z-Octadecenyl)-2-docosahexaenoyl-sn-glycero-3-phosphoethanolamine; Plasmenyl-PE (18:0/22:6); Plasmalogen PE (18:0/22:6); DHA-Plasmalogen Ethanolamine; 1-O-(Z-Octadec-1'-enyl)-2-docosahexaenoyl-sn-glycero-3-phosphoethanolamine
EINECS	Contact for details

Quality Control

Every batch of C18(Plasm)-22:6 Pe is manufactured under strict quality management systems and undergoes comprehensive analytical characterization to ensure identity, purity, and consistency. Our standard grade meets research-grade specifications with purity typically exceeding 95% (by HPLC). Certificates of Analysis (COA) detailing lot-specific results from NMR, MS, and HPLC analyses are provided with each shipment. Custom synthesis to meet specific purity or formulation requirements is available.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store unopened vials at -20°C or below under an inert atmosphere (argon or nitrogen). This product is hygroscopic (moisture-sensitive) and easily oxidized; allow the sealed vial to equilibrate to room temperature in a desiccator before opening to prevent condensation. Once opened, purge the container with inert gas and reseal immediately.

Specification

Item	Specification
Appearance	White to off-white waxy solid or oil
Identification (NMR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Solubility	Soluble in chloroform, ethanol, DMSO; insoluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.