Description

3-(Chloromethyl)Pyridine-2-Carbonitrile is a versatile and high-value pyridine derivative that serves as a critical building block in advanced organic synthesis. Its bifunctional nature, featuring both a reactive chloromethyl group and a nitrile moiety, makes it an indispensable intermediate for constructing complex heterocyclic systems. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of various drug candidates, particularly those targeting the central nervous system (CNS) and as kinase inhibitors.
• Agrochemical Synthesis: Used to construct pyridine-based herbicides, fungicides, and insecticides with enhanced efficacy.
• Ligand and Catalyst Development: Serves as a starting material for creating novel chelating ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Building block for synthesizing functionalized polymers and organic electronic materials.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes.
• Custom Synthesis and Contract Manufacturing: A high-demand intermediate for custom synthesis projects requiring specific pyridine functionalization.

Basic Information

Product Name	3-(Chloromethyl)Pyridine-2-Carbonitrile
CAS No.	205984-76-5
Molecular Formula	C7H5ClN2
Molecular Weight	152.58 g/mol
Synonyms	2-Cyano-3-(chloromethyl)pyridine; 3-(Chloromethyl)picolinonitrile; 2-Pyridinecarbonitrile, 3-(chloromethyl)-; Picolinonitrile, 3-(chloromethyl)-; (3-Chloromethyl-pyridin-2-yl)-acetonitrile; 3-Chloromethyl-2-cyanopyridine; 2-Cyanopyridin-3-ylmethyl chloride
EINECS	Contact for details

Quality Control

Our 3-(Chloromethyl)Pyridine-2-Carbonitrile is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP and ISO standards for manufacturing where required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.