Description

Vegfa Protein, Human CAS NO 205887-54-3 is a highly purified, recombinant human vascular endothelial growth factor A, a critical signaling protein essential for angiogenesis and vasculogenesis. This protein is vital for research and development in life sciences, serving as a key reagent to study cellular processes, disease mechanisms, and therapeutic interventions. It is primarily utilized by biotechnology firms, academic research institutions, and pharmaceutical companies engaged in cardiovascular research, cancer biology, and regenerative medicine.

Application

• Cell Culture & In Vitro Studies: Used as a growth factor supplement to promote the proliferation, migration, and survival of endothelial cells and other specific cell types.
• Angiogenesis Research: Essential for investigating the molecular mechanisms of blood vessel formation in both physiological and pathological contexts, such as tumor growth.
• Drug Discovery & Screening: Serves as a target or tool compound in high-throughput assays to identify and validate potential inhibitors or activators of the VEGF signaling pathway.
• Biomaterial & Tissue Engineering: Incorporated into scaffolds and hydrogels to enhance vascularization in engineered tissues and implants.
• Diagnostic Development: Utilized as a standard or calibrator in immunoassays (e.g., ELISA) to quantify VEGF levels in clinical or research samples.
• Signal Transduction Studies: Employed to activate VEGFR2 and downstream pathways (MAPK, PI3K/Akt) to study intracellular signaling cascades.

Basic Information

Product Name	Vegfa Protein, Human
CAS No.	205887-54-3
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Vascular Endothelial Growth Factor A (VEGF-A); VEGF165; VPF (Vascular Permeability Factor); Recombinant Human VEGF; rhVEGF-A; VEGF Isoform 165; VEGF165
EINECS	Contact for details

Quality Control

Our Vegfa Protein, Human is produced under stringent conditions to ensure high biological activity and batch-to-batch consistency. Each lot undergoes comprehensive analytical testing, including purity assessment, endotoxin level determination, and functional activity bioassays. Certificates of Analysis (COA) detailing specifications and test results are provided and available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C or below. Avoid repeated freeze-thaw cycles. This product is hygroscopic (moisture-sensitive).

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Purity (SDS-PAGE)	> 95%
Purity (HPLC)	> 98%
Endotoxin Level	< 1.0 EU/μg
Biological Activity	Determined by cell proliferation assay
Solubility	Soluble in water or PBS

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.