Description

n-Acetyl-D,L-Homotryptophan is a chemically modified derivative of the amino acid tryptophan, featuring an acetyl group and an extended methylene chain. This modification enhances its metabolic stability and makes it a valuable non-natural amino acid building block for advanced research and development. It is particularly sought after by pharmaceutical and biotechnology companies for applications in peptide synthesis and medicinal chemistry. The compound is supplied to meet the stringent quality requirements of industrial and research-scale production.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of novel therapeutic peptides and peptidomimetics.
• Biochemical Research: Used in metabolic pathway studies and as a probe to investigate enzyme specificity and function.
• Peptide Synthesis: Incorporated into custom peptide sequences to alter their physicochemical properties, stability, or biological activity.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in analytical laboratories.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to develop new drug candidates with optimized profiles.

Basic Information

Product Name	n-Acetyl-D,L-Homotryptophan
CAS No.	205813-00-9
Molecular Formula	C₁₄H₁₆N₂O₃
Molecular Weight	260.29 g/mol
Synonyms	N-Acetyl-DL-homotryptophan; Ac-DL-Hot-OH; 2-Acetamido-4-(1H-indol-3-yl)butanoic acid; DL-α-Acetamido-γ-(3-indolyl)butyric acid; N-Acetyl-3-(2-aminoethyl)indole-4-carboxylic acid (racemic); N-Acetyl-DL-2-amino-4-(3-indolyl)butyric acid; Racemic N-Acetylhomotryptophan
EINECS	Contact for details

Quality Control

Our n-Acetyl-D,L-Homotryptophan is manufactured under a quality management system. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing specifications such as assay, chiral purity, and impurity profiles is provided with every shipment to guarantee it meets your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.0%
Optical Purity (Chiral HPLC)	Racemic mixture (DL)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.