Description

4-Chloro-2-Trifluoroacetyl-6-Methoxyaniline is a high-purity, advanced pharmaceutical intermediate characterized by its distinct trifluoroacetyl and methoxy functional groups. This compound matters as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly those targeting central nervous system and inflammatory pathways. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel therapeutic agents and high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel APIs, especially in neurological and anti-inflammatory drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides with enhanced efficacy.
• Chemical Research & Development: Serves as a versatile precursor in organic synthesis for introducing the trifluoroacetyl moiety into complex molecules.
• Material Science: Potential building block for specialty polymers and advanced organic materials requiring specific electronic properties.
• Dye and Pigment Industry: Intermediate for synthesizing specialized dyes and pigments with unique colorfastness and stability.

Basic Information

Product Name	4-Chloro-2-Trifluoroacetyl-6-Methoxyaniline
CAS No.	205756-22-5
Molecular Formula	C9H7ClF3NO2
Molecular Weight	253.61 g/mol
Synonyms	2-Amino-5-chloro-3-methoxybenzotrifluoride; 5-Chloro-2-methoxy-α,α,α-trifluoroacetanilide; 4-Chloro-2-methoxy-6-(trifluoroacetyl)aniline; 4-Chloro-6-methoxy-2-(trifluoroacetyl)aniline; 2-Trifluoroacetyl-4-chloro-6-methoxyaniline; 1-Amino-5-chloro-3-methoxy-2-(trifluoroacetyl)benzene; 4-Chloro-2-(trifluoroacetyl)-6-methoxyaniline; 4-Chloro-6-methoxyaniline-2-trifluoromethyl ketone
EINECS	Contact for details

Quality Control

Our 4-Chloro-2-Trifluoroacetyl-6-Methoxyaniline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) are provided with every shipment, detailing all specifications and test results. We adhere to cGMP principles where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.