Description

Orexin B is a potent neuropeptide hormone that plays a critical role in regulating arousal, wakefulness, and appetite. Its high purity and consistent quality make it an essential research-grade material for advanced biochemical studies. This product is primarily utilized by pharmaceutical R&D teams, academic research institutions, and biotechnology companies focused on neuroscience, sleep disorders, and metabolic research.

Application

• Neuroscience Research: Used as a reference standard and active agent in studies investigating orexin receptor (OX2R) signaling pathways, neuronal excitability, and sleep/wake cycles.
• Pharmacological Studies: Employed in in vitro and in vivo assays to screen and evaluate potential therapeutic compounds targeting the orexin system for insomnia and narcolepsy.
• Biochemical Analysis: Serves as a critical component in receptor binding assays, functional cellular assays, and the development of diagnostic tools.
• Academic & Institutional Research: Provides a reliable, high-purity compound for fundamental research into neuroendocrine functions and related physiological processes.

Basic Information

Product Name	Orexin B
CAS No.	205599-76-4
Molecular Formula	C₉₉H₁₅₀N₂₈O₂₈S₂
Molecular Weight	2288.6 g/mol
Synonyms	Hypocretin-2; HCRT2; Orexin-B (human, rat, mouse); Hypocretin 2; Orexin B Peptide; Orexin-B, human; Prepro-orexin (131-178) (human); Orexin B (human); Orexin-B Precursor (131-178).
EINECS	Contact for details

Quality Control

Our Orexin B is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and peptide content determination, Mass Spectrometry (MS) for identity confirmation, and Amino Acid Analysis (AAA). A detailed Certificate of Analysis (COA) documenting all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dedicated freezer. The product is hygroscopic (moisture-sensitive). Allow the vial to reach room temperature in a desiccator before opening to minimize moisture absorption. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by AAA)
Water Content (KF)	≤ 5.0%
Acetate Content (HPIC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.