Description

Fmoc-(2-Inda)Gly-Oh is a protected amino acid derivative, specifically an Fmoc-protected glycine analog with a 2-indanyl side chain. This compound is a critical building block in solid-phase peptide synthesis (SPPS), enabling the controlled assembly of complex peptides and peptidomimetics. It is essential for researchers and manufacturers in pharmaceutical development, biotechnology, and advanced materials science who require high-purity, structurally defined intermediates for creating novel therapeutic agents and bioactive molecules.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key monomer for the automated, sequential construction of custom peptide sequences.
• Pharmaceutical Research & Development: Used in the discovery and synthesis of peptide-based drug candidates, including hormone analogs and enzyme inhibitors.
• Bioconjugation: Serves as a linker or spacer molecule for attaching peptides to other biomolecules, surfaces, or carriers.
• Combinatorial Chemistry: Employed in libraries for high-throughput screening to identify new bioactive compounds.
• Peptidomimetic Design: The 2-indanyl group provides a rigid, aromatic moiety useful for mimicking protein secondary structures and enhancing metabolic stability.
• Academic Research: A fundamental reagent for studying peptide structure-activity relationships and developing new synthetic methodologies.

Basic Information

Product Name	Fmoc-(2-Inda)Gly-Oh
CAS No.	205526-39-2
Molecular Formula	C₂₆H₂₃NO₄
Molecular Weight	413.46 g/mol
Synonyms	Fmoc-2-indanylglycine; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-2-indanylglycine; (2-{[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}-2-(2-indanyl)acetic acid); Fmoc-(2-Indanyl)Gly-OH; Fmoc-2-Inda-Gly-OH; N-Fmoc-2-indanylglycine; 2-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-2-(2-indanyl)acetic acid
EINECS	Contact for details

Quality Control

Our Fmoc-(2-Inda)Gly-Oh is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, typically meeting standards suitable for peptide synthesis. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support compliance with relevant guidelines for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.5%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.